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Merck

739979

Resomer® RG 858 S, Poly(D,L-lactide-co-glycolide)

ester terminated, lactide:glycolide 85:15, Mw 190,000-240,000

동의어(들):

PLGA

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
[C3H4O2]x[C2H2O2]y
CAS 번호:
26780-50-7
MDL number:
MFCD00131930
UNSPSC Code:
12162002
NACRES:
NA.23

주요 문서

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SMILES string

O2C(C(=O)OC(C2=O)C)C.O1CC(=O)OCC1=O

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

InChI key

LCSKNASZPVZHEG-UHFFFAOYSA-N

form

amorphous

feed ratio

lactide:glycolide 85:15

mol wt

Mw 190,000-240,000

degradation timeframe

<9 months

viscosity

1.3-1.7 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

storage temp.

2-8°C

Quality Level

100

관련 카테고리

General description

RESOMER® polymers are bioresorbable aliphatic polyesters comprised of a range of different ratios of lactide and glycolide monomers, PLA stereochemistries, and end-group functionalization. These biodegradeable homopolymers and copolymers of lactide and glycolide afford a variety of properties that range from very stiff, hard semi-crystalline materials with long degradation times, to softer, amorphous materials with faster degradation rates.

Application

Controlled release
Electrospun Resomer® X 206 S blended with cellulose from bagasse can be used as a scaffold in tissue engineering.

Features and Benefits

Controlled release of bioactive agents, sutures and bioabsorbable implantable devices.

Legal Information

Product of Evonik
RESOMER is a registered trademark of Evonik Rohm GmbH

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
MKCZ1409
MKCW7933
MKCV5197
BCCG7417
BCCF7604

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

RESOMER??Biodegradeable Polymers for Sutures, Medical Devices, Drug Delivery Systems and Tissue Engineering
Mader K
Material Matters, 6(3), 62-62 (2011)
Rongcai Liang et al.
International journal of pharmaceutics, 454(1), 344-353 (2013-07-23)
Peptide or protein degradation often occurs when water flows into the dosage form. The aim of this study was to investigate the effect of water on exenatide acylation in poly(lactide-co-glycolide) (PLGA) microspheres. Exenatide-loaded PLGA microspheres were incubated at different relative
Mani Gajendiran et al.
Colloids and surfaces. B, Biointerfaces, 104, 107-115 (2013-01-10)
A series of biodegradable low molecular weight PLGA-PEG-PLGA tri-block copolymers have been synthesized in powder form. The anti-tuberculosis drug Isoniazid (INH) loaded polymeric core-shell nanoparticles (CSNPs) have been prepared by sonication followed by water-in-oil-in-water (w/o/w) double emulsification technique. The nanoparticles
Vanna Sanna et al.
International journal of nanomedicine, 7, 5501-5516 (2012-10-25)
Resveratrol, like other natural polyphenols, is an extremely photosensitive compound with low chemical stability, which limits the therapeutic application of its beneficial effects. The development of innovative formulation strategies, able to overcome physicochemical and pharmacokinetic limitations of this compound, may
Shu-Chun Chuang et al.
Parasites & vectors, 6, 34-34 (2013-02-13)
Current development efforts of subunit vaccines against Toxoplasma gondii, the etiological agent of toxoplasmosis, have been focused mainly on tachyzoite surface antigen 1 (SAG1). Since microparticles made from poly (lactide-co-glycolide) (PLG) polymers have been developed as safe, potent adjuvants or
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문서

Bioprinting for Tissue Engineering and Regenerative Medicine

In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.

Biodegradable Aliphatic Polyesters for Drug Delivery

Innovations in polymer technology have had a significant impact on the advancement of novel drug delivery systems.

Poly(Glycerol Sebacate) in Tissue Engineering

Synthetic aliphatic polyesters dominate resorbable biomaterials in clinical use.

Biodegradable Polyester Nanoparticle Formation

AliAliphatic polyesters, including polylactide and polyglycolide, are biodegradable polymers widely used in medical applications.

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