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Merck

935425

Gelatin from cold water fish skin

low endotoxin

동의어(들):

Gelatin / GelMA & derivatives

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제품정보 (DICE 배송 시 비용 별도)

NACRES:
NA.21
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Quality Level

form

powder (chunks or fibers)

impurities

<10 CFU/g Bioburden (fungal), <10 CFU/g Bioburden (total aerobic), 125 EU/g Endotoxin

color

white to pale yellow

storage temp.

2-8°C

General description

Gelatin is widely used for tissue engineering and 3D Bioprinting applications. Gelatin is derived from natural extracellular matrix (ECM) components. Due to its low cost, abundance, and retention of natural cell binding motifs, gelatin has become a highly sought material for tissue engineering applications. While gelatin from porcine skin is known for its thermoreversible gelling properties, Gelatin from cold water fish skin has low gelling and melting points. This gelatin will not gel at 10°C, hence they do not have bloom strength. This unique gelatin property makes this an attractive biomaterial which are hindered by the higher thermogelation property of porcine skin such as vat-polymerization based bioprinting and microfluidics.

Application

  • Hydrogels
  • Tissue engineering
  • Bioprinting
  • Drug delivery system

Features and Benefits

  • Naturally derived polymer
  • Low gelling and melting points
  • Thermoreversible gelling properties
  • Low endotoxin and low bioburden
Low Endotoxin, low bioburden: Endotoxins have been demonstrated negatively impact cellular growth, morphology, differentiation, inflammation and protein expression. Bioburden is defined as the number of contaminated organisms found in a given amount of material. We test each lot for endotoxins as well as total bioburden (aerobic and fungal) to minimize unwanted interactions. For more information visit: Cell Culture FAQs: Bacterial Endotoxin Contamination


저장 등급

11 - Combustible Solids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable



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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문



Hee Jeong Yoon et al.
PloS one, 11(10), e0163902-e0163902 (2016-10-11)
Gelatin methacryloyl (GelMA) is a versatile biomaterial that has been used in various biomedical fields. Thus far, however, GelMA is mostly obtained from mammalian sources, which are associated with a risk of transmission of diseases, such as mad cow disease
Svetlana R Derkach et al.
Polymers, 12(12), 3051-3051 (2020-12-24)
This review considers the main properties of fish gelatin that determine its use in food technologies. A comparative analysis of the amino acid composition of gelatin from cold-water and warm-water fish species, in comparison with gelatin from mammals, which is
Abudureheman Maihemuti et al.
Bioactive materials, 26, 77-87 (2023-03-07)
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