F2456
Fluorescein (free acid)
Dye content 95%, Powder
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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C20H12O5
CAS 번호:
Molecular Weight:
332.31
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
Colour Index Number:
45350:1
EC Number:
219-031-8
MDL number:
Beilstein/REAXYS Number:
94324
제품 이름
Fluorescein (free acid), Dye content 95 %
form
powder
Quality Level
composition
Dye content, 95%
technique(s)
titration: suitable
color
orange to red-brown
mp
320 °C (lit.)
λmax
496 nm
ε (extinction coefficient)
≥12000 at 282-286 nm, ≥39000 at 236-240 nm, ≥70000 at 488-492 nm
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
Oc1ccc2c(Oc3cc(O)ccc3C24OC(=O)c5ccccc45)c1
InChI
1S/C20H12O5/c21-11-5-7-15-17(9-11)24-18-10-12(22)6-8-16(18)20(15)14-4-2-1-3-13(14)19(23)25-20/h1-10,21-22H
InChI key
GNBHRKFJIUUOQI-UHFFFAOYSA-N
General description
Fluorescein (free acid, CI 45350) is a xanthene dye. Fluorescein (free acid) molecule can be divided into two parts. One part contains xanthene moiety which acts as fluorophore and the other part of the molecule bears benzene moiety which is the fluorescence-controlling moiety.
Application
Fluorescein (free acid) has been used as a staining agent in retinal imaging.
Fluorescein (free acid) is widely used as a fluorescent stain and trace for many living cells and tissue applications. It is also suitable as a marker for the study of motility of bile canaliculi. Some of the clinical applications are evaluating the ocular surface and delineation of brain regions lacking a blood-brain barrier to permit accurate surgical resection of malignant glioma. Fluorescein angiography helps investigate changes in retinal blood supply. Fluorescein also plays a role as a physiological tracer to characterize the salmon′s intestinal permeability (Schep et al., 1998), and for the fluorophotometric measurement of aqueous humor flow. It is widely employed as a quantum yield standard.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Eye Irrit. 2
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Cunyang Wang et al.
Materials science & engineering. C, Materials for biological applications, 103, 109823-109823 (2019-07-28)
Acrylic bone cement (ABC) has been used as a grouting agent in joint replacement surgery for over 50 years. In particular, ABC is irreplaceable for high-load joint replacement such as total hip joint replacements (THJRs) and total knee joint replacements because
Tasuku Ueno et al.
Journal of the American Chemical Society, 126(43), 14079-14085 (2004-10-28)
Rational design strategies based on practical fluorescence modulation mechanisms would enable us to rapidly develop novel fluorescence probes for target molecules. Here, we present a practical and general principle for modulating the fluorescence properties of fluorescein. We hypothesized that (a)