H1384
Hypotaurine
≥98% (TLC)
동의어(들):
2-Aminoethanesulfinic acid
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크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C2H7NO2S
CAS 번호:
Molecular Weight:
109.15
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
≥98% (TLC)
Quality Segment
assay
≥98% (TLC)
color
white to off-white
solubility
H2O: 100 mg/mL
SMILES string
NCCS(O)=O
InChI
1S/C2H7NO2S/c3-1-2-6(4)5/h1-3H2,(H,4,5)
InChI key
VVIUBCNYACGLLV-UHFFFAOYSA-N
Application
Hypotaurine has been used as a supplement in fertilization medium (Fert- tyrode albumin lactate pyruvate (TALP)), which used in in-vitro fertilization and evaluation of embryo development. It is also used as a H2S scavenger.
Biochem/physiol Actions
Antioxidant that binds hydroxyl radicals. Endogenous inhibitory neuromodulator that is blocked by strychnine and picrotoxin. Inhibits the Na2+-dependent transport of GABA and β-alanine. It is a degradation product of cysteine and a precursor of taurine.
Hypotaurine, a cystamine analog, is the precursor for taurine synthesis. It can act as an antioxidant and singlet oxygen scavenger, thereby protecting cells from oxidative damage. Hypotaurine is reported to play an important role in the maintenance and stimulation of sperm motility and also in vitro fertilization and embryo development.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
저장 등급
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
Protective effect of hypotaurine against oxidative stress-induced cytotoxicity in rat placental trophoblasts.
Nishimura T
Placenta, 36(6), 693-698 (2015)
Andrea Carenzo et al.
Cells, 9(8) (2020-08-07)
Oral premalignant lesions (OPLs) represent the most common oral precancerous conditions. One of the major challenges in this field is the identification of OPLs at higher risk for oral squamous cell cancer (OSCC) development, by discovering molecular pathways deregulated in
Ultrastructural and immunohistochemical characterization of the bovine epiblast.
Vejlsted M, et al.
Biology of Reproduction, 72(3), 678-686 (2005)