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Merck

W421501

Tyramine

98%, FG

동의어(들):

2-(4-Hydroxyphenyl)ethylamine, 4-(2-Aminoethyl)phenol, 4-Hydroxyphenethylamine

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
HOC6H4CH2CH2NH2
CAS 번호:
Molecular Weight:
137.18
Flavis number:
11.007
PubChem Substance ID:
UNSPSC Code:
12164502
FEMA Number:
4215
NACRES:
NA.21
EC Number:
200-115-8
MDL number:
Beilstein/REAXYS Number:
1099914
Organoleptic:
meaty; phenolic
Grade:
FG
Biological source:
synthetic
Food allergen:
no known allergens
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biological source

synthetic

Quality Level

grade

FG

reg. compliance

EU Regulation 1334/2008 & 872/2012, FDA 21 CFR 110

assay

98%

bp

175-181 °C/8 mmHg (lit.)

mp

160-162 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

meaty; phenolic

SMILES string

NCCc1ccc(O)cc1

InChI

1S/C8H11NO/c9-6-5-7-1-3-8(10)4-2-7/h1-4,10H,5-6,9H2

InChI key

DZGWFCGJZKJUFP-UHFFFAOYSA-N

Biochem/physiol Actions

Can enter catecholaminergic terminals and be released as a false transmitter.


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Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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문서 라이브러리 방문



M G Bianchetti et al.
Klinische Wochenschrift, 60(9), 465-470 (1982-05-03)
Responses of blood pressure and plasma catecholamines to intravenous injection of tyramine at increasing dosage (30, 45, and 60 microgram/kg, respectively) were evaluated in 25 normal subjects and 20 patients with mild essential hypertension. Basal plasma norepinephrine and epinephrine concentrations
Moussa B H Youdim et al.
Neurotoxicology, 25(1-2), 243-250 (2003-12-31)
The major side effect with the use of first generation of non selective monoamine oxidase (MAO) inhibitors as neuropsychiatric drugs was what became known as the "cheese reaction". Namely, potentiation of sympathomimetic activity of ingested tyramine present in cheese and
Stephan A Chalon et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 28(9), 1685-1693 (2003-06-05)
Evidence suggests that compounds that increase the synaptic availability of more than one neurotransmitter have greater efficacy in the treatment of depression than single-acting drugs. Preclinical studies indicate that duloxetine acts to inhibit serotonin (5-HT) and norepinephrine (NE) transporters. The