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Merck

850458P

Avanti

16:0-18:2 PC

Avanti Research - A Croda Brand

동의어(들):

1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine; PC(16:0/18:2(9Z,12Z))

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C42H80NO8P
CAS 번호:
Molecular Weight:
758.06
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
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제품 이름

16:0-18:2 PC, 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 2 × 100 mg (850458P-200mg), pkg of 1 × 25 mg (850458P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850458P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O

InChI

1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1

InChI key

JLPULHDHAOZNQI-ZTIMHPMXSA-N

General description

16:0-18:2 PC or 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine is a glycerophospholipid, with substitution of palmitic acid and linolenic acid at sn-1 and sn-2 positions of the glycerol backbone, respectively.

Application

16:0-18:2 PC or 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine:
  • has been used in liposomes for standard cell-free translation
  • has been used in the extraction of serum lipids and in peroxisome proliferator-activated receptor-δ (PPAR-δ) assay
  • might be used to study the effects of phosphatidylcholines (PCs) on lubrication of damaged mesothelium

Packaging

5 mL Clear Glass Sealed Ampule (850458P-200mg)
5 mL Clear Glass Sealed Ampule (850458P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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문서 라이브러리 방문



Giulia Coliva et al.
Molecules (Basel, Switzerland), 25(8) (2020-04-25)
Free radical driven lipid peroxidation is a chain reaction which can lead to oxidative degradation of biological membranes. Propagation vs. termination rates of peroxidation in biological membranes are determined by a variety of factors including fatty acyl chain composition, presence
Lindsay Kosack et al.
Scientific reports, 7(1), 11289-11289 (2017-09-14)
Lipid metabolism is increasingly being appreciated to affect immunoregulation, inflammation and pathology. In this study we found that mice infected with lymphocytic choriomeningitis virus (LCMV) exhibit global perturbations of circulating serum lipids. Mice lacking the lipid-sensing surface receptor triggering receptor
John K Eaton et al.
Nature chemical biology, 16(5), 497-506 (2020-04-02)
We recently described glutathione peroxidase 4 (GPX4) as a promising target for killing therapy-resistant cancer cells via ferroptosis. The onset of therapy resistance by multiple types of treatment results in a stable cell state marked by high levels of polyunsaturated