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Merck

D-061

11-Deoxycortisol solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C21H30O4
CAS 번호:
152-58-9
Molecular Weight:
346.46
NACRES:
NA.24
PubChem Substance ID:
329798624
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
MFCD00003662

주요 문서

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InChI key

WHBHBVVOGNECLV-OBQKJFGGSA-N

InChI

1S/C21H30O4/c1-19-8-5-14(23)11-13(19)3-4-15-16(19)6-9-20(2)17(15)7-10-21(20,25)18(24)12-22/h11,15-17,22,25H,3-10,12H2,1-2H3/t15-,16+,17+,19+,20+,21+/m1/s1

SMILES string

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@@]4(C)[C@H]3CC[C@]4(O)C(=O)CO

grade

certified reference material

Quality Level

300

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

format

single component solution

storage temp.

−20°C

관련 카테고리

General description

A new calibration material suitable for multiple LC/MS applications in clinical and diagnostic testing and endocrinology. An immediate precursor to cortisol, 11-deoxycortisol, or cortodoxone, is measured in whole blood by LC-MS/MS for newborn screening of congenital adrenal hyperplasia (CAH) and in serum or plasma by LC-MS/MS for determination of several diseases including Cushing′s syndrome, pituitary tumor, and Addison′s disease.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

저장 등급

3 - Flammable liquids

wgk

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Brett C McWhinney et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(28), 2863-2869 (2010-09-21)
We describe an ultra high performance liquid chromatography-tandem mass spectrometry (UHPLC MS/MS) method suitable for a routine laboratory to determine endogenous and exogenous glucocorticoids in plasma, plasma ultrafiltrate, urine and saliva in a single analytical run. After addition of a
A 2-year-old boy with a testicular mass. Diagnosis: testicular tumor of adrenogenital syndrome due to 11-beta-hydroxylase deficiency.
Tolga Unuvar et al.
Pediatric annals, 39(8), 471-474 (2010-08-14)
Lamprey endocrinology is not ancestral.
Joseph W Thornton et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(2), E5-E5 (2011-01-07)
Michael E Baker et al.
Steroids, 76(13), 1451-1457 (2011-08-16)
The serum of Atlantic sea lamprey, a basal vertebrate, contains two corticosteroids, 11-deoxycortisol and deoxycorticosterone. Only 11-deoxycortisol has high affinity [K(d) ~ 3 nM] for the corticoid receptor [CR] in lamprey gill cytosol. To investigate the binding of 11-deoxycortisol to
Jacqueline Jonklaas et al.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 18(1), 66-75 (2011-08-23)
To determine whether the time of day at which corticotropin stimulation testing is performed influences the steroid concentrations observed in persons with normal adrenal function. In this retrospective, secondary analysis, participants with normal adrenal function were studied to determine whether
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