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Merck

07-585

Anti-dimethyl-Histone H3 (Arg2) Antibody

serum, Upstate®

동의어(들):

H3R2me2, Histone H3 (di methyl R2)

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크기 선택


제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
polyclonal
Species reactivity:
human, chicken
Application:
WB, inhibition assay
Citations:
18
기술 서비스
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도움 문의

biological source

rabbit

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, chicken

manufacturer/tradename

Upstate®

technique(s)

inhibition assay: suitable (peptide), western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

dimethylation (Arg2)

Quality Level

Gene Information

human ... H3F3B(3021)

General description

Mr 17kDa

Immunogen

peptide containing the sequence AdimRT, corresponding to dimethyl-arginine 2 of human histone H3

Application

Anti-dimethyl-Histone H3 (Arg2) Antibody is a Rabbit Polyclonal Antibody for detection of dimethyl-Histone H3 (Arg2) also known as H3R2me2, Histone H3 (di methyl R2) & has been validated in WB, PIA.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones

Biochem/physiol Actions

Broad species cross-reactivity expected
dimethyl-arginine at residue 2 of histone H3

Physical form

Serum
rabbit antiserum containing 0.05% sodium azide, before the addition of glycerol to 30%

Preparation Note

2 years at -20°C

Analysis Note

routinely evaluated by immunoblot on acid-extracted proteins from chicken erythrocyte cells (Catalog # 13-107)

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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저장 등급

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


시험 성적서(COA)

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Sinja Rakow et al.
Methods (San Diego, Calif.), 175, 53-65 (2019-09-23)
Among the widespread and increasing number of identified post-translational modifications (PTMs), arginine methylation is catalyzed by the protein arginine methyltransferases (PRMTs) and regulates fundamental processes in cells, such as gene regulation, RNA processing, translation, and signal transduction. As epigenetic regulators
PELP1 oncogenic functions involve alternative splicing via PRMT6.
Mann, M; Zou, Y; Chen, Y; Brann, D; Vadlamudi, R
Molecular Oncology null
Jihee Hong et al.
Journal of ginseng research, 46(3), 481-488 (2022-05-24)
Although the tumor-suppressive effects of ginsenosides in cell cycle have been well established, their pharmacological properties in mitosis have not been clarified yet. The chromosomal instability resulting from dysregulated mitotic processes is usually increased in cancer. In this study, we
Haolin Liu et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(37), E7717-E7726 (2017-08-30)
Two of the unsolved, important questions about epigenetics are: do histone arginine demethylases exist, and is the removal of histone tails by proteolysis a major epigenetic modification process? Here, we report that two orphan Jumonji C domain (JmjC)-containing proteins, JMJD5
Futaba Inoue et al.
International journal of oncology, 64(3) (2024-02-01)
Histone modification, a major epigenetic mechanism regulating gene expression through chromatin remodeling, introduces dynamic changes in chromatin architecture. Protein arginine methyltransferase 6 (PRMT6) is overexpressed in various types of cancer, including prostate, lung and endometrial cancer (EC). Epigenome regulates the expression

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