ligand
(Sulfoethyl)
Quality Segment
product line
Fractogel®
form
resin
specific analyte(s)
MAbs
parameter
220 cm/hr flow rate, 8 bar max. pressure
matrix active group
methacrylate
mean particle size
40-90 μm
capacity
160 mg binding capacity (lysozyme/ml of resin)
transition temp
flash point 35 °C (calculated)
application(s)
recombinant protein
vaccine development
separation technique
cation exchange, strong cation exchange
storage temp.
2-30°C
General description
Strong cation exchange Fractogel® resin featuring the tentacle technology, for purification of basic and neutral proteins (e.g. antibodies) and peptides
Features and Benefits
Fractogel® EMD SE Hicap (M) features include:
- Tentacle technology provides high yield, selectivity, and focused elution
- High loading capacity combined with high purity at lower elution volumes
- Compatibility with 2.5 % (v/v) aqueous benzyl alcohol containing 150 mM NaCl storage solution
Packaging
- 1.14894.0100: Fractogel® EMD SE Hicap (M) Resin 100ml
- 1.14894.0010: Fractogel® EMD SE Hicap (M) Resin 10ml
- 1.14894.0500: Fractogel® EMD SE Hicap (M) Resin 500ml
- 1.14894.5000: Fractogel® EMD SE Hicap (M) Resin 5L
Plastic bottle
Analysis Note
Appearance: Milky turbid suspension,free from impurities(foreign particles)
Microscopic evaluation: Uniform spherical particles,no agglomerates,no fines
Extractable matter (water): ≤ 0.08 %
Cerium: ≤ 20 µg/g
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 1.0 bar
Particle size (d10): 37 - 45 µm
Particle size (d50): 48 - 60 µm
Particle size (d90): 63 - 77 µm
Colony forming units (TAMC + TYMC): ≤ 100 CFU/ml
Endotoxins: ≤ 1.00 EU/ml
Protein binding capacity (lysozyme): 120 - 160 mg/ml
Functional test (b:a): ≤ 0.20
Functional test: Separation of chymotrypsinogen A and lysozyme
Microscopic evaluation: Uniform spherical particles,no agglomerates,no fines
Extractable matter (water): ≤ 0.08 %
Cerium: ≤ 20 µg/g
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 1.0 bar
Particle size (d10): 37 - 45 µm
Particle size (d50): 48 - 60 µm
Particle size (d90): 63 - 77 µm
Colony forming units (TAMC + TYMC): ≤ 100 CFU/ml
Endotoxins: ≤ 1.00 EU/ml
Protein binding capacity (lysozyme): 120 - 160 mg/ml
Functional test (b:a): ≤ 0.20
Functional test: Separation of chymotrypsinogen A and lysozyme
Legal Information
FRACTOGEL is a registered trademark of Merck KGaA, Darmstadt, Germany
Still not finding the right product?
Explore all of our products under Fractogel® EMD SE Hicap (M)
signalword
Warning
hcodes
Hazard Classifications
Flam. Liq. 3
저장 등급
3 - Flammable liquids
Emprove® 프로그램을 사용하여 GMP 준수 유지
Emprove® Dossiers로 자격을 가속화하고, 규정 준수를 유지하며, 시간을 절약하세요.
Dossiers 다운로드
주: EmproveSuite.com으로 이동하게 됩니다. 귀하의 사용자 이름과 비밀번호는 시그마알드리치닷컴과는 별개이며 다를 수 있습니다.
무료로 등록하고 몇 분 안에 Emprove® Dossiers에 액세스하세요. 구독 플랜을 업그레이드하여 Emprove® Suite에서 고급 및 맞춤형 콘텐츠를 잠금 해제하세요.
원하는 정보를 찾지 못하셨나요? Emprove® 프로그램 도움말 페이지 방문하기.
