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Merck

12666

Albumin, Human Serum, Fraction V, Low Heavy Metals

동의어(들):

Albumin, Human Serum, Fraction V, Low Heavy Metals

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제품정보 (DICE 배송 시 비용 별도)

CAS 번호:
UNSPSC Code:
12352202
NACRES:
NA.25
MDL number:
eCl@ss:
42010201
Assay:
≥95% (SDS-PAGE)
Form:
solid
Impurities:
≤5.0% Ash, ≤6% moisture
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SMILES string

FC(F)(F)C(F)(F)C(F)(F)F

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI key

QYSGYZVSCZSLHT-UHFFFAOYSA-N

description

Merck USA index - 14, 8468

assay

≥95% (SDS-PAGE)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

impurities

≤5.0% Ash, ≤6% moisture

pI 

4.7

solubility

water: 50 mg/mL

cation traces

heavy metals: ≤20 ppm

shipped in

ambient

Quality Level

storage temp.

2-8°C

General description

Human serum albumin (HSA) is an abundant protein found in the plasma. This globular, soluble, and unglycosylated monomeric protein, has three homologous domains (I, II, and III). These domains have subdomains A and B having common structural motifs. The HSA gene is located on the human chromosome 4q13.3.

Application

Albumin, Human Serum, Fraction V, Low Heavy Metals has been used:
  • as a supplement in double buffer and milliQ-water for in vivo
  • in serum-free media for polarized secretion assays in human dermal microvascular endothelial cells
  • as a supplement in sodium phosphate buffer for the reconstitution of hormone lysis samples

Biochem/physiol Actions

Human serum albumin (HSA) is very crucial in stabilizing extracellular fluid volume. It functions as an excipient for vaccines and therapeutic protein drugs. HSA serves as a cell culture medium supplement for the synthesis of vaccines and pharmaceuticals. It is useful as a carrier protein for steroids, fatty acids, and thyroid hormones. HSA is used to treat cardiopulmonary bypass, trauma, hemorrhage, and hypoalbuminemia. HSA is useful in biological applications, such as implantable biomaterials, biochromatography, surgical adhesives, and sealants.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Toxicity: Standard Handling (A)

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Chanchal Sadhu et al.
Journal of immunology (Baltimore, Md. : 1950), 170(5), 2647-2654 (2003-02-21)
Neutrophil chemotaxis is a critical component of the innate immune response. Neutrophils can sense an extremely shallow gradient of chemoattractants and produce relatively robust chemotactic behavior. This directional migration requires cell polarization with actin polymerization occurring predominantly in the leading
Tina Jorsal et al.
The Journal of clinical endocrinology and metabolism, 104(12), 6403-6416 (2019-07-06)
After Roux-en-Y gastric bypass (RYGB) surgery, postprandial plasma glucagon concentrations have been reported to increase. This occurs despite concomitant improved glucose tolerance and increased circulating plasma concentrations of insulin and the glucagon-inhibiting hormone glucagon-like peptide 1 (GLP-1). To investigate whether
C J Kelley et al.
Microbiology spectrum, 10(6), e0360122-e0360122 (2022-11-08)
As multidrug and pan-resistance among Enterobacterales continue to increase, there is an urgent need for more therapeutic options to treat these infections. New β-lactam and β-lactam inhibitor (BLI) combinations have a broad spectrum of activity, but those currently approved do
Stephan Schmidt et al.
Antimicrobial agents and chemotherapy, 52(11), 3994-4000 (2008-09-10)
During antibiotic drug development, media are frequently spiked with either serum/plasma or protein supplements to evaluate the effect of protein binding. Usually, previously reported serum or plasma protein binding values are applied in the analysis. The aim of this study
Rune Ehrenreich Kuhre et al.
Journal of molecular endocrinology, 56(3), 201-211 (2016-01-29)
GLUTag, NCI-H716, and STC-1 are cell lines that are widely used to study mechanisms underlying secretion of glucagon-like peptide-1 (GLP-1), but the extent to which they resemble native L-cells is unknown. We used validated immunoassays for 14 different hormones to

국제 무역 품목 번호

SKUGTIN
12666-100GMCN04055977222807
12666-10GMCN04055977222791
12666-1GMCN04055977222777

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