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Merck

3741

Hemin Chloride

Iron-containing compound of porcine origin that can induce hydrogen peroxide-dependent lipid peroxidation. Reported to increase the number and size of myotubes and the frequency of myotube contractions.

동의어(들):

Hemin Chloride

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제품정보 (DICE 배송 시 비용 별도)

CAS 번호:
NACRES:
NA.21
UNSPSC Code:
12352202
MDL number:
Form:
solid
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Quality Level

description

Merck USA index - 14, 4644

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

dark purple

solubility

0.1-1.0 M NaOH: soluble, 1 N NH4OH: soluble

shipped in

ambient

storage temp.

15-25°C

InChI

1S/C34H34N4O4.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);/q;+3/p-2

InChI key

GGIDWJQWCUJYRY-UHFFFAOYSA-L

General description

Iron containing compound of porcine origin that can induce H2O2-dependent lipid peroxidation. Reported to increase the number and size of myotubes and the frequency of myotube contractions. Induces heme-oxygenase-1 activity and reduces renal injury induced by mercuric compounds.
Iron-containing compound of porcine origin that can induce hydrogen peroxide-dependent lipid peroxidation. Reported to increase the number and size of myotubes and the frequency of myotube contractions.

Application


  • Porphyrins ameliorate spinocerebellar ataxia type 36 GGCCTG repeat expansion-mediated cytotoxicity: Discusses the therapeutic potentials of hemin chloride in neurological disorders, highlighting its role in mitigating cytotoxic effects associated with genetic mutations, significant for advancing neurodegenerative disease treatments (Hirayanagi K et al., 2021).

  • Indirect Quantification of Glyphosate by SERS Using an Incubation Process With Hemin as the Reporter Molecule: A Contribution to Signal Amplification Mechanism: Demonstrates the application of hemin chloride in enhancing signal detection in spectroscopic analysis, important for improving analytical methods in environmental and food sciences (López-Castaños KA et al., 2020).

Preparation Note

Unstable in solution; reconstitute just prior to use.

Analysis Note

homogeneous by TLC

Other Notes

Yonega, R., et al. 2000. Toxicol. Lett.116, 223.
Funanage, V.L., et al. 1989. J. Cell. Physiol.141, 591.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)


저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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문서 라이브러리 방문



Kristine Y Tan et al.
The Analyst, 145(10), 3732-3741 (2020-04-30)
In an open microfluidic device, we investigate protein polyacrylamide gel electrophoresis (PAGE) separation performance on single-cell lysate. Single-cell protein electrophoresis is performed in a thin layer of polyacrylamide (PA) gel into which microwells are molded. Individual cells are isolated in



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SKUGTIN
3741-5GMCN04055977191196