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Merck

48-681MAG

MILLIPLEX® Multi-Pathway Signaling Panel

Premixed Multi-Pathway Total 9-Plex Cell Signaling Panel

동의어(들):

Luminex® Cell Signaling Assay, Millipore Cell Signaling Assay, Signal Transduction Panel, MAPK STAT TCR assay, multi-pathway signaling panel, multi-target phosphorylation panel, phosphoprotein multiplex assay, rat cell signaling panel, rat intracellular signaling biomarkers

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제품정보 (DICE 배송 시 비용 별도)

NACRES:
NA.47
UNSPSC Code:
12161503
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제품 이름

MILLIPLEX® Multi-Pathway Signaling Panel,

Quality Level

description

Premixed Multi-Pathway Total 9-Plex Cell Signaling Panel

species reactivity

human, mouse, rat

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

technique(s)

multiplexing: suitable

input

cell lysate

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

This panel includes total proteins from multiple signaling pathways that regulate cell survival, proliferation, inflammation, and transcriptional activity. ERK1/2, JNK, and p38 are core components of the MAPK pathway involved in stress and growth responses. Akt regulates cell survival and metabolism. NFκB controls inflammatory and immune signaling. STAT3 and STAT5A/B mediate cytokine-driven transcriptional regulation. CREB is a transcription factor activated by cAMP signaling, and p70 S6 Kinase plays a role in protein synthesis and cell growth. Quantifying these total proteins supports pathway profiling and comparative analysis across experimental conditions.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 9 analytes in human, mouse, or rat cell lysate samples.

Analytes Included: ERK/MAPK 1/2, Akt, STAT3, JNK, p70 S6 Kinase, NFκB, STAT5A/B, CREB, p38

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate Control Assays).

Features and Benefits

  • Simultaneously detect 9 total proteins across key signaling pathways
  • Covers MAPK, STAT, Akt, NFκB, and CREB pathways for broad cellular profiling
  • Magnetic bead-based format ensures reproducibility and efficient processing
  • Compatible with cell lysates from diverse experimental conditions
  • Ideal for signal transduction, oncology, immunology, and toxicology research
  • Fast, convenient alternative to Western blotting and immunoprecipitation procedures

Legal Information

Luminex is a registered trademark of Luminex Corp
MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.


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Danger

저장 등급

10 - Combustible liquids

wgk

WGK 3

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - ED ENV 1 - Eye Dam. 1 - Skin Irrit. 2



시험 성적서(COA)

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관련 콘텐츠

Discover the benefits of MILLIPLEX® multiplex assays, based on Luminex® xMAP® multiplex assay technology, that provide consistent, high-quality results and see how these multiplex biomarker Luminex® assays are being used to advance research.

Learn how multiplexing with MILLIPLEX® multiplex assays can help simplify cancer research by measuring multiple circulating biomarkers at once. Find multiplex panels to analyze JAK-STAT, mTOR, MAPK, SAPK, TGFβ signaling pathways, and more.

Uncover how cells communicate with MILLIPLEX® cell signaling multiplex assays. Multiplexing with cell signaling phosphoprotein assays based on Luminex® xMAP® technology helps researchers measure phosphoproteins and total proteins within the same or different pathways from a single sample.

관련 콘텐츠 모두 보기

Poonam Naik et al.
Translational vision science & technology, 10(9), 26-26 (2021-08-24)
Infections with multidrug-resistant Pseudomonas aeruginosa (MDR-PA) lead to poor clinical outcomes in endophthalmitis patients, and its interactions with the host immune system remain largely unknown. The current study aimed to determine the association of MDR-PA infection with the cytokine expression
Fabrízio Dos Santos Cardoso et al.
Frontiers in cellular neuroscience, 15, 683127-683127 (2021-09-21)
Aging is often accompanied by exacerbated activation of cell death-related signaling pathways and decreased energy metabolism. We hypothesized that transcranial near-infrared laser may increase intracellular signaling pathways beneficial to aging brains, such as those that regulate brain cell proliferation, apoptosis
James P McNamee et al.
International journal of radiation biology, 97(9), 1316-1323 (2021-05-29)
To assess the effects of 1800 MHz radiofrequency electromagnetic field (RF-EMF) exposure on the expression of signal transduction and antioxidant proteins in a human-derived A172 glioblastoma cell line. Adherent human-derived A172 glioblastoma cells (1.0 × 105 cells per 35 mm culture dish, containing 2 mL



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SKUGTIN
48-681MAG04055977168792