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Merck

48-684MAG

MILLIPLEX® Ras-Raf Oncoprotein Signaling Panel

Premixed Human Ras-Raf Oncoprotein 6-Plex Cell Signaling Panel

동의어(들):

Cell Signaling Assay, MAPK cascade assay, MEK1/ERK1/2 panel, Raf kinase assay, Ras pathway ELISA, Ras-Raf assay, Ras-Raf phosphoprotein panel, oncogene signaling multiplex, phospho-Raf

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제품정보 (DICE 배송 시 비용 별도)

NACRES:
NA.47
UNSPSC Code:
12161503
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제품 이름

MILLIPLEX® Ras-Raf Oncoprotein Signaling Panel,

description

Premixed Human Ras-Raf Oncoprotein 6-Plex Cell Signaling Panel

species reactivity

human

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

technique(s)

multiplexing: suitable

input

cell lysate

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

This panel targets phosphorylated proteins in the Ras-Raf signaling cascade, a key pathway in cell proliferation and oncogenesis. It includes c-Raf (pS338), MEK1 (pS217/pS221), ERK1/2 (pT185/pY187), and downstream effectors such as p90RSK (pT359/pS363). Dysregulation of this pathway is commonly associated with various cancers, making this panel ideal for oncology and signal transduction research.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 6 analytes in cell lysate samples.

Analytes Included: c-Raf (Phospho-Ser338), MEK1 (Phospho-Ser217/221), ERK1/2 (Phospho-Thr185/Tyr187), p90RSK (Phospho-Thr359/Ser363)

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate Control Assays).

Features and Benefits

  • Simultaneously detect 6 phosphorylated proteins in the Ras-Raf-MEK-ERK signaling cascade
  • Includes c-Raf, MEK1, ERK1/2, and p90RSK
  • Magnetic bead-based format ensures reproducibility and efficient processing
  • Compatible with cell lysates from cancer, proliferation, and signal transduction studies
  • Ideal for oncology, targeted therapy research, and MAPK pathway analysis
  • Fast, convenient alternative to Western Blotting and immunoprecipitation procedures"

Legal Information

Luminex is a registered trademark of Luminex Corp
MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use indiagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which containsfluorescently labeled microsphere beads authorized by Luminex Corporation) orusing this Assay Product in any manner, you are consenting and agreeing to bebound by the End User Terms and Conditions and the End User License Agreementavailable at http://support.diasorin.com/end-user-terms-and-conditions/. If youdo not agree to all of the terms and conditions, you must promptly return thisAssay Product for a full refund prior to using it in any manner.


signalword

Danger

저장 등급

10 - Combustible liquids

wgk

WGK 3

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - ED ENV 1 - Eye Dam. 1 - Skin Irrit. 2



시험 성적서(COA)

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관련 콘텐츠

Learn how multiplexing with MILLIPLEX® multiplex assays can help simplify cancer research by measuring multiple circulating biomarkers at once. Find multiplex panels to analyze JAK-STAT, mTOR, MAPK, SAPK, TGFβ signaling pathways, and more.

Uncover how cells communicate with MILLIPLEX® cell signaling multiplex assays. Multiplexing with cell signaling phosphoprotein assays based on Luminex® xMAP® technology helps researchers measure phosphoproteins and total proteins within the same or different pathways from a single sample.





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SKUGTIN
48-684MAG04061841049098