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4995

Ouabain octahydrate

≥95% (HPLC), solid, Na⁺,K⁺-ATPase inhibitor, Calbiochem®

동의어(들):

Ouabain, Octahydrate, Strophanthin G

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C29H44O12 · 8H2O
CAS 번호:
11018-89-6
Molecular Weight:
728.77
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD00149240
Assay:
≥95% (HPLC)
Form:
solid
Quality level:
100
Storage condition:
OK to freeze, protect from light
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제품 이름

Ouabain, Octahydrate, Inhibits Na+,K+-ATPase.

Quality Level

100

description

RTECS - RN3850000
Merck USA index - 14 6901

assay

≥95% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

white to off-white

solubility

hot water: 10 mg/mL, room-temperature water: insoluble

shipped in

ambient

storage temp.

2-8°C

SMILES string

O1CC(=CC1=O)[C@@H]2C3(C(C4[C@H]([C@@H](C3)O)C5([C@@H](C[C@@H](CC5(CC4)O)OC6OC(C(C(C6O)O)O)C)O)CO)(CC2)O)C.O.O.O.O.O.O.O.O

InChI

1S/C29H44O12.8H2O/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31;;;;;;;;/h7,13,15-19,21-25,30-32,34-38H,3-6,8-12H2,1-2H3;8*1H2/t13?,15-,16+,17?,18+,19+,21+,22?,23?,24?,25?,26?,27?,28?,29?;;;;;;;;/m0......../s1

InChI key

TYBARJRCFHUHSN-HMNHGHQSSA-N

General description

Inhibits Na+ and K+-dependent ATPases. Has cardiotonic properties.
Inhibits Na+,K+-ATPase. Exhibits cardiotonic properties. Preferentially enhances radiotoxicity in tumor cells and induces apoptosis by prolonging the irradiation-induced G2 delay.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Na+,K+-ATPase
Product does not compete with ATP.
Reversible: no

Preparation Note

Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 2 weeks at 4°C or for up to 2 months at -20°C.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Verheye-Dua, F.A., and Bohm, L. 2000. Strahlenther Onkol. 176, 186.
Hasenauer, J., et al. 1993. J. Biol. Chem.268, 3289.
Rakowski, F.F. 1993. J. Gen. Physiol.101, 117.
Mahaney, J.E., and Grisham, C.M. 1992. Biochemistry31, 2025.
Xu, Z.J., et al. 1992. J. Physiol.456, 405.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Toxic (F)

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pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 1 Oral - Acute Tox. 3 Inhalation - STOT RE 2

저장 등급

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

시험 성적서(COA)

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국제 무역 품목 번호

SKUGTIN
4995-1GMCN04055977199253