AM80
Anti-PAR (Ab-1) Mouse mAb (10H)
liquid, ≥95% (SDS-PAGE), clone 10H
동의어(들):
Anti-Poly (ADP-Ribose)
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
10H, monoclonal
Species reactivity:
human, Drosophila, rat, mouse
Application:
—
Citations:
31
biological source
mouse
antibody form
purified antibody
antibody product type
primary antibodies
clone
10H, monoclonal
assay
≥95% (SDS-PAGE)
form
liquid
contains
≤0.1% sodium azide as preservative
species reactivity
human, Drosophila, rat, mouse
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
dilution
(Immunoblotting (2.5 µg/mL)
Immunocytochemistry (5-20 µg/mL))
isotype
IgG3
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
General description
Protein A purified mouse monoclonal antibody. Recognizes poly-ADP-ribose.
Recognizes poly(ADP)-ribose (PAR) in etopside-treated HL-60 cells.
This Anti-PAR (Ab-1) Mouse mAb (10H) is validated for use in Immunoblotting, Immunocytochemistry for the detection of PAR (Ab-1).
Immunogen
Bovine
purified poly(ADP-ribose)
Application
Immunoblotting (2.5 µg/ml)
Immunocytochemistry (5-20 µg/ml)
Immunocytochemistry (5-20 µg/ml)
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In 100 mM NaCl, 50 mM HEPES, 1% BSA, pH 7.4.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Analysis Note
Negative Control
Normal mouse IgG
Normal mouse IgG
Positive Control
Etoposide-treated HL-60 cells
Etoposide-treated HL-60 cells
Other Notes
Kawamitsu, H., et al. 1984. Biochemistry23, 3771.
PAR can be induced in HL-60 cells by treatment with 67 µM etoposide for 3.5 h. Antibody should be titrated for optimal results in an individual system.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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저장 등급
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Laura Maggi et al.
European journal of immunology, 40(8), 2174-2181 (2010-05-21)
We have previously shown that human Th17 lymphocytes are characterized by the selective expression of IL-23 receptor (IL-23R), CCR6, CD161, and the transcription factor retinoic acid-related orphan receptor C (RORC), and originate from a CD161(+)CD4(+) naïve T-cell precursor in response
Gautier Stoll et al.
Oncoimmunology, 8(6), e1571389-e1571389 (2019-05-10)
The expression of two metabolic enzymes, i.e., aldehyde dehydrogenase 7 family, member A1 (ALDH7A1) and lipase C, hepatic type (LIPC) by malignant cells, has been measured by immunohistochemical methods in non-small cell lung carcinoma (NSCLC) biopsies, and has been attributed
Li-Li Zhuang et al.
PloS one, 8(10), e77304-e77304 (2013-11-10)
All-trans retinoic acid (ATRA) is an active metabolite of Vitamin A, it shows protective effects on asthma, including maintains airway epithelial integrity, inhibits asthma effector cells differentiation, modulates immune response, et al. However, the promoting effect of ATRA on Th2
Young-Ok Son et al.
Toxicology and applied pharmacology, 255(3), 287-296 (2011-07-20)
Cadmium is a toxic heavy metal which is environmentally and occupationally relevant. The mechanisms underlying cadmium-induced autophagy are not yet completely understood. The present study shows that cadmium induces autophagy, as demonstrated by the increase of LC3-II formation and the
J Wang et al.
Oncogene, 36(43), 5939-5947 (2017-06-27)
Understanding the mechanisms of platinum compound resistance, including cisplatin resistance, has important implications for improving cancer treatments. Previous studies identified a potential role for mitogen-activated protein kinase phosphatase-1 (MKP-1) in cisplatin resistance. This work focuses on the regulation of poly(ADP-ribose)
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| AM80-100UGCN | 04055977228052 |
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