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Merck

CP35

Anti-PSD-95 (Ab-2) Mouse mAb (7E3-1B8)

liquid, clone 7E3-1B8, Calbiochem®

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제품정보 (DICE 배송 시 비용 별도)

NACRES:
NA.43
UNSPSC Code:
12352203
Clone:
7E3-1B8, monoclonal
Species reactivity:
rat
Application:
Citations:
15
기술 서비스
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도움 문의
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도움 문의

biological source

mouse

antibody form

purified antibody

antibody product type

primary antibodies

clone

7E3-1B8, monoclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

rat

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

dilution

(Immunoblotting (1:2000)
Immunofluorescence (1:200, indirect)
Immunoprecipitation )

isotype

IgG2a

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

rat ... Dlg4(29495)

General description

Purified mouse monoclonal antibody generated by immunizing BALB/c mice with the specified immunogen and fusing splenocytes with HL-1 mouse myeloma cells (see application references). Recognizes the ~95 kDa PSD-95 protein.
Recognizes the ~95 kDa PSD95 protein.
This Anti-PSD-95 (Ab-2) Mouse mAb (7E3-1B8) is validated for use in Immunoblotting, Immunofluorescence, Immunoprecipitation for the detection of PSD-95 (Ab-2).

Immunogen

Rat
recombinant, rat PSD95

Application


Immunoblotting (1:2000)
Immunofluorescence (1:200, indirect)
Immunoprecipitation (see comments)

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In PBS.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Brakeman, P.R., et al. 1997. Nature386, 284.
Hualing, D., et al. 1997. Nature386, 279.
Kennedy, M.B. 1997. Trends in Neurosci.20, 264.
Sanes, J. 1997. Curr. Opin. Neurobiol.7, 93.
Cho., K.-O., et al. 1992. Neuron9, 929.
Immunofluorescent staining of rat hippocampal cells shows a staining pattern coincident with NMDA receptor staining at synaptic sites consistent with PSD-95′s proposed role in receptor clustering. This antibody has also been reported to work for immunoprecipitation. Fixation with cold methanol is recommended for immunofluorescence. Antibody should be titrated for optimal results in individual systems.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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저장 등급

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Sabrina Reinehr et al.
International journal of molecular sciences, 20(10) (2019-05-30)
Studies have suggested an involvement of the immune system in glaucoma. Hence, a rat experimental autoimmune glaucoma model (EAG) was developed to investigate the role of the immune response. Here, we transferred this model into mice. Either 0.8 mg/mL of
Hanyu Fu et al.
Acta physiologica (Oxford, England), 239(1), e14009-e14009 (2023-06-18)
General anesthesia can induce cognitive deficits in both humans and rodents, correlating with pathological alterations in the hippocampus. However, whether general anesthesia affects olfactory behaviors remains controversial as clinical studies have produced inconsistent results. Therefore, we aimed to investigate how
Han-Yu Fu et al.
Brain pathology (Zurich, Switzerland), 33(2), e13114-e13114 (2022-09-06)
Reactive astrogliosis and neuronal death are major features of brain tissue damage after transient global cerebral ischemia/reperfusion (I/R). The CA1 subfield in the hippocampus is particularly susceptible to cell death after I/R. Recently, attention has focused on the relationship between
Luisa Fernanda Toro-Fernández et al.
Frontiers in cellular neuroscience, 15, 643717-643717 (2021-11-19)
Glutamate excitotoxicity triggers overactivation of CDK5 and increases calcium influx in neural cells, which promotes dendritic retraction, spine loss, increased mitochondrial calcium from the endoplasmic reticulum, and neuronal death. Our previous studies showed that CDK5 knockdown (KD) in astrocytes improves
Jessica L Cifelli et al.
The Journal of biological chemistry, 291(23), 11981-11992 (2016-03-30)
The majority of excitatory synapses in the brain exist on dendritic spines. Accordingly, the regulation of dendritic spine density in the hippocampus is thought to play a central role in learning and memory. The development of novel methods to control

국제 무역 품목 번호

SKUGTIN
CP35-100ULCN04055977220988

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