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Merck

MAB3101

Anti-Connexin 45 Antibody, near CT, cytoplasmic, clone 5B9.2

clone 5B9.2, Chemicon®, from mouse

동의어(들):

Cx45

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
5B9.2, monoclonal
Application:
ICC, WB
Citations:
9
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도움 문의

Quality Level

biological source

mouse

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

5B9.2, monoclonal

species reactivity

rat, rabbit, human

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable, western blot: suitable

isotype

IgG1

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... GJC1(10052)
rat ... Gjc1(266706)

Immunogen

The peptide sequence used for the immunogen was H-Gln-Ala-Tyr-Ser-His-Gln-Asn-Asn-Pro-His-Gly-Pro-Arg-Glu-Cys-OH conjugated to KLH, corresponding to amino acids 354-367 of human connexin 45.
Epitope: near C-terminus, cytoplasmic

Application

Anti-Connexin 45 Antibody, near C-terminus, cytoplasmic, clone 5B9.2 detects level of Connexin 45 & has been published & validated for use in IC & WB.
Immunblotting (~46 kDa)

Immunocytochemistry

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters

Biochem/physiol Actions

Recognizes Human Connexin 45.

SPECIES REACTIVITIES:

Due to sequence homologies, this antibody is also expected to react with canine (100% homology) and mouse (92% homology) Connexin 45. Also confirmed to work on rat C6 cells. Others not tested.

Physical form

Format: Purified
Liquid at 1 mg/mL in 0.02M PB with 0.25 M NaCl, pH=7.6 containing 0.1% sodium azide.

Preparation Note

Maintain at 2-8°C in undiluted aliquots for up to 12 months.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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당사의 제품 선택기 도구.을(를) 시도해 보세요.

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

저장 등급

12 - Non Combustible Liquids


시험 성적서(COA)

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

J I Nagy et al.
The European journal of neuroscience, 46(2), 1790-1804 (2017-06-01)
Electrical synapses formed by connexin36 (Cx36)-containing gap junctions between interneurons in the cerebellar cortex have been well characterized, including those formed between basket cells and between Golgi cells, and there is gene reporter-based evidence for the expression of connexin45 (Cx45)
Axonal synapses utilize multiple synaptic ribbons in the mammalian retina.
Kim, HL; Jeon, JH; Koo, TH; Lee, UY; Jeong, E; Chun, MH; Moon, JI; Massey, SC; Kim, IB
Testing null
Hideo Hoshi et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 29(28), 8875-8883 (2009-07-17)
The vertebrate retina is a distinctly laminar structure. Functionally, the inner plexiform layer, in which bipolar cells synapse onto amacrine and ganglion cells, is subdivided into two sublaminae. Cells that depolarize at light offset ramify in sublamina a; those that
Richard Fischer et al.
Gastroenterology, 128(2), 433-448 (2005-02-03)
Gap junctional communication was studied in quiescent and activated hepatic stellate cells. Connexin expression and intercellular dye transfer were studied in rat hepatic stellate cells in culture and in vivo. Protein expression of connexin 43 was up-regulated in activated hepatic
John E Rash et al.
Journal of neurocytology, 34(3-5), 307-341 (2006-07-15)
Odorant/receptor binding and initial olfactory information processing occurs in olfactory receptor neurons (ORNs) within the olfactory epithelium. Subsequent information coding involves high-frequency spike synchronization of paired mitral/tufted cell dendrites within olfactory bulb (OB) glomeruli via positive feedback between glutamate receptors

국제 무역 품목 번호

SKUGTIN
MAB310104053252614477

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