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Merck

NE1019

Anti-Myelin Basic Protein Mouse mAb (SMI-99)

liquid, clone SMI-99, Calbiochem®

동의어(들):

Myelin basic protein antibody

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제품정보 (DICE 배송 시 비용 별도)

NACRES:
NA.43
UNSPSC Code:
12352203
Clone:
SMI-99, monoclonal
Species reactivity:
guinea pig (weakly), mammals
Application:
Citations:
22
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biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

SMI-99, monoclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

guinea pig (weakly), mammals

should not react with

chicken, porcine

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

dilution

(ELISA (1:1000)
Immunoblotting (1:1000)
Immunocytochemistry (1:1000)
Frozen Sections (1:1000)
Paraffin Sections (1:1000))

isotype

IgG2b

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MBP(4155)

General description

Recognizes the ~21 kDa myelin basic protein in rat brain tissue. Does not recognize the 14 kDa form. Recognizes most mammalian species.
This Anti-Myelin Basic Protein Mouse mAb (SMI-99) is validated for use in ELISA, Immunoblotting, Immunocytochemistry, Frozen Sections, Paraffin Sections for the detection of Myelin Basic Protein.
Purified mouse monoclonal antibody. Recognizes the ~21 kDa myelin basic protein (MBP).

Immunogen

Epitope: Within amino acids 131-136
human myelin basic protein

Application


ELISA (1:1000)
Immunoblotting (1:1000)
Immunocytochemistry (1:1000)
Frozen Sections (1:1000)
Paraffin Sections (1:1000)

Other Notes

Evers, P. and Uylings, H.B. 1997. J. Neurosci. Methods72, 197.
Shin, R.W., et al. 1991. Lab. Invest.64, 693.
Recognizes MBP from most mammalian species. Does not recognize the ~14 kDa form of MBP. Detects developing and adult myelin and developing oligodendrocytes. Also distinguishes oligodendrocytes from astrocytes, microglia, neurons, and other cells in brain tissue sections. In combination with Anti-Myelin Basic Protein Mouse mAb (SMI-91) (Cat. No. NE1020) and/or Anti-Myelin Basic Protein Mouse mAb (SMI-94) (Cat. No. NE1018) this antibody is useful for immunocytochemical studies on the progression of normal and pathologic myelination. Antibody should be titrated for optimal results in individual systems.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)


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저장 등급

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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문서 라이브러리 방문



Jane L Zhu et al.
Journal of translational medicine, 20(1), 41-41 (2022-01-26)
Morphea is an autoimmune, sclerosing skin disorder. Despite the recent emphasis on immune dysregulation in morphea, the role of autoantibodies in morphea pathogenesis or utility as biomarkers are poorly defined. Autoantigen microarray was used to profile autoantibodies from the serum
Gerben van Hameren et al.
Acta neuropathologica communications, 7(1), 86-86 (2019-06-13)
Mitochondria are critical for the function and maintenance of myelinated axons notably through Adenosine triphosphate (ATP) production. A direct by-product of this ATP production is reactive oxygen species (ROS), which are highly deleterious for neurons. While ATP shortage and ROS
Michela Losurdo et al.
Brain sciences, 10(4) (2020-04-16)
Traumatic brain injury (TBI) commonly results in primary diffuse axonal injury (DAI) and associated secondary injuries that evolve through a cascade of pathological mechanisms. We aim at assessing how myelin and oligodendrocytes react to head angular-acceleration-induced TBI in a previously



국제 무역 품목 번호

SKUGTIN
NE1019-100ULCN04055977209884