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Merck

10107409001

Roche

Mitomycin C

crystalline powder, 98%, pkg of 2 mg

동의어(들):

Mitomycin C

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C15H18N4O5
CAS 번호:
50-07-7
Molecular Weight:
334.33
MDL number:
MFCD00078109
UNSPSC Code:
12352207
NACRES:
NA.54

주요 문서

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SMILES string

N21[C@]([C@H]4N[C@H]4C2)([C@@H](C3=C1C(=O)C(=C(C3=O)N)C)COC(=O)N)OC

InChI

1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1

InChI key

NWIBSHFKIJFRCO-WUDYKRTCSA-N

assay

98%

form

crystalline powder

mol wt

334.3

packaging

pkg of 2 mg

manufacturer/tradename

Roche

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

mode of action

DNA synthesis | interferes

storage temp.

2-8°C

관련 카테고리

General description

Mitomycin C is an antitumor antibiotic.

Application

Mitomycin C has been used:
  • to cease mitosis
  • in phosphate buffer saline (PBS) for inactivation and plating mouse embryonic fibroblasts (MEFs)
  • as mutagen in mutagenicity assay

Mitomycin C is used as an inhibitor for studies of cell-free protein biosynthesis. It also inhibits DNA synthesis. It has been used as a genotoxic agent for tumor cells.

Biochem/physiol Actions

Mitomycin C (MMC) acts as a prototype for drugs with bioreductive alkylation. It is mainly found to be active under anaerobic conditions. MMC exhibits a vast clinical antitumor spectrum effectively in gastric, pancreatic and breast cancer.

Other Notes

For life science research only. Not for use in diagnostic procedures.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

hcodes

H300,H351

Hazard Classifications

Acute Tox. 2 Oral - Carc. 2

저장 등급

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

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시험 성적서(COA)

Lot/Batch Number
66178900
62669600
46983900
40496900
38475000

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