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Merck

16033

1,2-Propanediol

meets analytical specification of Ph. Eur., BP, USP, ≥99.5%

동의어(들):

1,2-PDO, Propylene glycol

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
CH3CH(OH)CH2OH
CAS 번호:
57-55-6
Molecular Weight:
76.09
UNSPSC Code:
12352100
NACRES:
NA.21
PubChem Substance ID:
57647543
EC Number:
200-338-0
Beilstein/REAXYS Number:
1340498
MDL number:
MFCD00064272
Assay:
≥99.5%
Form:
liquid

주요 문서

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InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

SMILES string

CC(O)CO

vapor density

2.62 (vs air)

vapor pressure

0.08 mmHg ( 20 °C)

assay

≥99.5%

form

liquid

autoignition temp.

779 °F

quality

meets analytical specification of Ph. Eur., BP, USP

shelf life

24 mo.

expl. lim.

12.5 %

impurities

acidic reac. impurities, complies, organic volatile impurities, complies (GC), oxidizing substances, complies, reducing matter, complies, residual solvents, complies, ≤0.0005% heavy metals (as Pb), ≤0.002% free alkali (as NaOH), ≤0.003% free acid (as CH3COOH), ≤0.2% water (Karl Fischer)

ign. residue

≤0.005% (as SO4)

refractive index

n20/D 1.431-1.433, n20/D 1.432 (lit.)

Quality Level

200

mp

−60 °C (lit.)

density

1.036 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

suitability

complies for appearance of solution

functional group

hydroxyl

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관련 카테고리

General description

1,2-Propanediol is an 1,2-alkanediol. It can be obtained from glycerol, via hydrogenolysis in the presence of Ru/C and Amberlyst ion-exchange resins.
1,2-Propanediol is an important petrochemical that can be prepared by the hydrogenolysis of glycerol. It is mainly used as a cryoprotectant for biological samples and also as an additive in food, cosmetic and pharmaceutical industries.

Application

1,2-Propanediol may be employed as a cryoprotective agent for the preservation (by cooling to sub-zero temperatures) of human embryos and and oocytes (human and mouse).

Packaging

bottled under inert gas

Other Notes

The article number 16033-4X5L will be discontinued. Please order the single bottle 16033-5L which is physically identical with the same exact specifications.
The article number 16033-6X1L will be discontinued. Please order the single bottle 16033-1L which is physically identical with the same exact specifications.
The article number 16303-4X2.5L-R will be discontinued. Please order the single bottle 16303-2.5L-R which is physically identical with the same exact specifications.

저장 등급

10 - Combustible liquids

flash_point_f

219.2 °F - closed cup

flash_point_c

104 °C - closed cup

ppe

Eyeshields, Gloves

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
SDBB6925
SDBB6486
SDBB3396
SDBB2967
SDBB2966

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

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문서 라이브러리 방문

Aqueous phase hydrogenolysis of glycerol to 1, 2-propanediol without external hydrogen addition.
Roy D, et al.
Catalysis Today, 156(1), 31-37 (2010)
B Lassalle et al.
Fertility and sterility, 44(5), 645-651 (1985-11-01)
Eighty-five human embryos fertilized in vitro were frozen and thawed with 1,2 propanediol as a cryoprotective agent. The effects of viability of in vitro culture duration, stage, and morphologic appearance of embryos were examined after thawing. Survival was higher for
Glycerol hydrogenolysis to 1, 2-propanediol catalyzed by a heat-resistant ion-exchange resin combined with Ru/C.
Miyazawa T, et al.
Applied Catalysis A: General, 329, 30-35 (2007)
D A Gook et al.
Human reproduction (Oxford, England), 8(7), 1101-1109 (1993-07-01)
Human and mouse oocytes were cryopreserved by a slow freeze, rapid thaw method, using propanediol (PROH) as the cryoprotectant. A simulated cryopreservation was also included in the study to detect the level of damage attributable to the PROH alone. Comparison
Mohammad Chand Ali et al.
Talanta, 203, 16-22 (2019-06-17)
The efficient extraction of natural products from biomass is deemed an essential area of interest using green technology in the pharmaceutical and biochemical industries. In recent years, deep eutectic solvents (DESs) have been paying broad interest as compatible, safe, and
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