341088
1,9-Dimethyl-Methylene Blue zinc chloride double salt
Dye content 80 %
동의어(들):
DMMB, Taylor’s Blue
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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C18H22ClN3S · 0.5ZnCl2
CAS 번호:
Molecular Weight:
416.05
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
form
powder
Quality Level
composition
Dye content, 80%
technique(s)
titration: suitable
impurities
<20% water
mp
250 °C (dec.) (lit.)
λmax
649 nm
ε (extinction coefficient)
≥10000 at 243-249 nm in H2O, ≥18000 at 285-291 nm in H2O, ≥25000 at 594-600 nm in H2O, ≥35000 at 646-652 nm in H2O
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
[Cl-].[Cl-].Cl[Zn]Cl.CN(C)c1cc(C)c2N=C3C(C)=C\C(C=C3Sc2c1)=[N+](/C)C.CN(C)c4cc(C)c5N=C6C(C)=C\C(C=C6Sc5c4)=[N+](/C)C
InChI
1S/2C18H22N3S.4ClH.Zn/c2*1-11-7-13(20(3)4)9-15-17(11)19-18-12(2)8-14(21(5)6)10-16(18)22-15;;;;;/h2*7-10H,1-6H3;4*1H;/q2*+1;;;;;+2/p-4
InChI key
MKLBAKXCEQNMBC-UHFFFAOYSA-J
Application
DMMB is a cationic dye that specifically binds to sulfated glycosaminoglycans (sGAG) with an absorbance at ~525 nm.
DMMB is a cationic dye that specifically binds to sulfated glycosaminoglycans (sGAG) with an absorbance at ~525 nm. It has been used to quantitate glycosaminoglyans such as chondroitin sulfate, keratin sulfate, and heparan sulfate and sGAG chains in proteoglycans. One limitation to this method The sGAG-DMMB complex is unstable in solution and may precipitate. Precipitation of the complex was shown to improve stability.
1,9-Dimethyl-Methylene Blue zinc chloride double salt has been used for the quantification of sulfated glycosaminoglycans.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Eye Irrit. 2
저장 등급
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
A Herrero-Mendez et al.
Journal of tissue engineering and regenerative medicine, 10(12), 1000-1011 (2014-03-07)
Biomaterials and, especially, scaffolds may function as temporary extracellular matrix (ECM), mimicking in vivo environmental structures and facilitating cell growth and tissue regeneration. ECM is composed mostly of glycosaminoglycans (GAGs) and proteins, the ratio of GAGs, hyaluronic acid (HA):sulphated GAGs
Hyeon-Son Choi et al.
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The anti-osteoarthritic activity of the methanol fraction of deer bone oil extract (DBO-M) was evaluated in interleukin (IL)-1β-inflamed primary rabbit chondrocytes and in rats with monosodium iodoacetate (MIA)-induced osteoarthritis. The active compound in DBO-M was analyzed using a direct infusion
High-throughput bone and cartilage micropellet manufacture, followed by assembly of micropellets into biphasic osteochondral tissue.
Babur BK
Cell and Tissue Research, 361(3), 755-768 (2015)