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Merck

B0301

Biotin

meets USP testing specifications

동의어(들):

D-Biotin, Bios II, Coenzyme R, Vitamin B7, Vitamin H

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C10H16N2O3S
CAS 번호:
Molecular Weight:
244.31
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
34058011
UNSPSC Code:
12352201
EC Number:
200-399-3
MDL number:
Beilstein/REAXYS Number:
86838
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biological source

synthetic (organic)

Quality Level

agency

meets USP testing specifications

assay

97.5-102.0%

form

powder

color

white

mp

231-233 °C (lit.)

application(s)

pharmaceutical (small molecule)

storage temp.

2-8°C

SMILES string

[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2

InChI

1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

InChI key

YBJHBAHKTGYVGT-ZKWXMUAHSA-N

Application

<ul>
<li><strong>Protein Biotinylation Studies:</strong> Advanced strategies for biotinylation site characterization in proteins are being developed using biotin, improving the precision of protein modification techniques critical for biochemical research and drug development (Zhu, 2024).</li>
</ul>

Biochem/physiol Actions

Essential vitamin that is important for amino acid and energy metabolism, and fatty acid synthesis. It is a prosthetic group in four mammalian carboxylase families and facilitates the binding and transfer of carbon dioxide.


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저장 등급

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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시험 성적서(COA)

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문서 라이브러리 방문


문서

Importance and uses of biotin in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures


Konstantinos Ampatzis et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(26), 10875-10886 (2013-06-28)
In vertebrates, spinal circuits drive rhythmic firing in motoneurons in the appropriate sequence to produce locomotor movements. These circuits become active early during development and mature gradually to acquire the flexibility necessary to accommodate the increased behavioral repertoire of adult
A Limat et al.
Archives of dermatological research, 288(1), 31-38 (1996-01-01)
In humans and in animals, biotin deficiency causes pathological changes in the skin and its appendages. High doses of biotin may also have beneficial effects on skin, hair and fingernails in humans and animals with normal biotin status. Therefore, we
Stuart Trenholm et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(37), 14927-14938 (2013-09-13)
Recently, we demonstrated that gap junction coupling in the population of superior coding ON-OFF directionally selective ganglion cells (DSGCs) genetically labeled in the Hb9::eGFP mouse retina allows the passage of lateral anticipatory signals that help track moving stimuli. Here, we