C9481
Carboxymethylcellulose sodium
meets USP testing specifications, Medium viscosity
동의어(들):
Carboxymethylcellulose sodium salt, Sodium carboxymethylcellulose
SMILES string
[Na].OC(C(O)C(O)C=O)C(O)CO.OC(=O)C
InChI
1S/C6H12O6.C2H4O2.Na/c7-1-3(9)5(11)6(12)4(10)2-8;1-2(3)4;/h1,3-6,8-12H,2H2;1H3,(H,3,4);
InChI key
DPXJVFZANSGRMM-UHFFFAOYSA-N
agency
USP/NF, meets USP testing specifications
assay
6.5-9.5% anhydrous basis (Sodium)
form
powder
color
light yellow
pH
(10 g/L68 °F neutral)
viscosity
400-800 cP, 2 % in H2O(25 °C)(lit.)
mp
> 300.05 °C ((> 572.09 °F ))
solubility
water: soluble
Quality Level
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General description
Carboxymethylcellulose sodium is a viscous polysaccharide that belongs to a high molecular weight category. It has mucoadhesive property and is used during eye surgery. Carboxymethylcellulose sodium promotes re-epithelialization of the epithelial cells in corneal wounds. It is useful for the study of attached cell and three-dimensional tissue culture models.
Application
Carboxymethylcellulose sodium has been used as a vehicle for tamoxifen citrate, sorafenib, and savolitinib. It has also been used as a component of serum-free medium (SFM) for the suspension of human umbilical vein endothelial spheroids.
Useful for the study of attached cell and three-dimensional tissue culture models.
Other Notes
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
저장 등급
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Carboxymethylcellulose binds to human corneal epithelial cells and is a modulator of corneal epithelial wound healing
Garrett Q, et al.
Investigative Ophthalmology & Visual Science, 48(4), 1559-1567 (2007)
Anti-estrogen resistance in human breast tumors is driven by JAG1-NOTCH4-dependent cancer stem cell activity
Simoes BM, et al.
Testing, 12(12), 1968-1977 (2015)
Vascular CXCR4 expression promotes vessel sprouting and sensitivity to sorafenib treatment in hepatocellular carcinoma
Xu J, et al.
Clinical Cancer Research, 23(15), 4482-4492 (2017)
The MET inhibitor AZD6094 (Savolitinib, HMPL-504) induces regression in papillary renal cell carcinoma patient-derived xenograft models
Schuller AG, et al.
Clinical Cancer Research, 21(12), 2811-2819 (2015)
Recent advances in modified cellulose for tissue culture applications
Courtenay J, et al.
Molecules (Basel), 23(3), 654-654 (2018)
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