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Merck

D6003

Digoxin

analytical standard

동의어(들):

12β-Hydroxydigitoxin

조직 및 계약 가격을 보려면 로그인를 클릭합니다.

크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C41H64O14
CAS 번호:
20830-75-5
Molecular Weight:
780.94
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329798818
EC Number:
244-068-1
Beilstein/REAXYS Number:
77011
MDL number:
MFCD00003674

주요 문서

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기술 서비스
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도움 문의

InChI key

LTMHDMANZUZIPE-PUGKRICDSA-N

InChI

1S/C41H64O14/c1-19-36(47)28(42)15-34(50-19)54-38-21(3)52-35(17-30(38)44)55-37-20(2)51-33(16-29(37)43)53-24-8-10-39(4)23(13-24)6-7-26-27(39)14-31(45)40(5)25(9-11-41(26,40)48)22-12-32(46)49-18-22/h12,19-21,23-31,33-38,42-45,47-48H,6-11,13-18H2,1-5H3/t19-,20-,21-,23-,24+,25-,26-,27+,28+,29+,30+,31-,33+,34+,35+,36-,37-,38-,39+,40+,41+/m1/s1

SMILES string

C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@H]2[C@@H](O)C[C@@H](O[C@@H]2C)O[C@H]3[C@@H](O)C[C@@H](O[C@@H]3C)O[C@H]4CC[C@@]5(C)[C@H](CC[C@@H]6[C@@H]5C[C@@H](O)[C@]7(C)[C@H](CC[C@]67O)C8=CC(=O)OC8)C4

biological source

plant (Digitalis lanata)

grade

analytical standard

assay

≥95.0% (HPLC)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

solubility

methanol: methylene chloride (1:1): 0.5%, clear, colorless

application(s)

food and beverages
forensics and toxicology
veterinary

format

neat

functional group

ketone

shipped in

ambient

storage temp.

room temp

Quality Level

100

Gene Information

human ... ATP1A1(476), ATP1A2(477), ATP1A3(478), ATP1A4(480), ATP1B1(481), ATP1B2(482), ATP1B3(483), FXYD2(486)

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관련 카테고리

Application

Digoxin may be used as an analytical reference standard for the quantification of the analyte in biological samples using chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

A cardiac glycoside, substrate for Pgp, upregulates Pgp expression and down regulates SXR (Steroid Xenobiotic Receptor).
A cardiac glycoside, substrate for Pgp.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 2 Oral - Acute Tox. 3 Inhalation - STOT RE 2

저장 등급

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
BCCN5223
BCCF1947
BCCM5546
BCCD9767
BCCD4453

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Combined liquid chromatography/radioimmunoassay with improved specificity for serum digoxin
Gault H.M, et al.
Clinical Chemistry, 31(8), 1272-1277 (1985)
Simultaneous determination of digoxin and permeability markers in rat in situ intestinal perfusion samples by RP-HPLC
Varma.S.V M, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 813(1-2), 347-352 (2004)
Kovi Bessoff et al.
Antimicrobial agents and chemotherapy, 57(4), 1804-1814 (2013-02-06)
Cryptosporidiosis, a diarrheal disease usually caused by Cryptosporidium parvum or Cryptosporidium hominis in humans, can result in fulminant diarrhea and death in AIDS patients and chronic infection and stunting in children. Nitazoxanide, the current standard of care, has limited efficacy
Melanie L Lawrence et al.
Scientific reports, 5, 9092-9092 (2015-03-15)
Recent advances in renal tissue engineering have shown that dissociated, early renogenic tissue from the developing embryo can self-assemble into morphologically accurate kidney-like organs arranged around a central collecting duct tree. In order for such self-assembled kidneys to be useful
Adriana Katz et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(44), 13723-13728 (2015-10-21)
The ciliary epithelium in the eye consists of pigmented epithelial cells that express the α1β1 isoform of Na,K-ATPase and nonpigmented epithelial cells that express mainly the α2β3 isoform. In principle, a Na,K-ATPase inhibitor with selectivity for α2β3 that penetrates the
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