G6529
L-Glutathione reduced
≥98.0%, BioXtra
동의어(들):
γ-L-Glutamyl-L-cysteinyl-glycine, GSH
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제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
H2NCH(CO2H)CH2CH2CONHCH(CH2SH)CONHCH2CO2H
CAS 번호:
Molecular Weight:
307.32
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
200-725-4
MDL number:
Beilstein/REAXYS Number:
1729812
제품 이름
L-Glutathione reduced, BioXtra, ≥98.0%
product line
BioXtra
Quality Segment
assay
≥98.0%
form
powder
impurities
≤0.02% Phosphorus (P), ≤0.1% Insoluble matter
ign. residue
≤0.1%
color
white
mp
192-195 °C (dec.) (lit.)
solubility
H2O: 0.1 M, clear, colorless
anion traces
sulfate (SO42-): ≤0.05%
cation traces
Al: ≤0.0005%, Ca: ≤0.02%, Cu: ≤0.0005%, Fe: ≤0.001%, K: ≤0.005%, Mg: ≤0.001%, NH4+: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%
storage temp.
2-8°C
SMILES string
N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
InChI
1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1
InChI key
RWSXRVCMGQZWBV-WDSKDSINSA-N
Application
May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.
Biochem/physiol Actions
Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.
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저장 등급
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)