K2012
Ketoprofen
meets USP testing specifications
동의어(들):
2-(3-Benzoylphenyl)propionic acid
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크기 선택
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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C16H14O3
CAS 번호:
Molecular Weight:
254.28
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
244-759-8
MDL number:
Quality Level
agency
USP/NF, meets USP testing specifications
form
solid
application(s)
pharmaceutical (small molecule)
SMILES string
CC(C(O)=O)c1cccc(c1)C(=O)c2ccccc2
InChI
1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)
InChI key
DKYWVDODHFEZIM-UHFFFAOYSA-N
Gene Information
human ... ALB(213), IL8RA(3577), PTGS1(5742), PTGS2(5743)
Application
- A strong, silk protein-inspired tissue adhesive with an enhanced drug release mechanism for transdermal drug delivery.: Although not exclusively focused on ketoprofen, this study details a novel adhesive for transdermal delivery, highlighting methods that could be adapted for enhancing the delivery of ketoprofen, thus being of interest to biochemists specializing in transdermal drug formulations (Fang et al., 2024).
Biochem/physiol Actions
Non-steroidal anti-inflammatory compound that is selective for COX-1.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2
저장 등급
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Elisabeth Christiansen et al.
Journal of medicinal chemistry, 54(19), 6691-6703 (2011-08-23)
The free fatty acid receptor 1 (FFA1, also known as GPR40) enhances glucose-stimulated insulin secretion from pancreatic β-cells and is recognized as an interesting new target for treatment of type 2 diabetes. Several series of selective FFA1 agonists are already
Ikram Ullah Khan et al.
International journal of pharmaceutics, 441(1-2), 809-817 (2012-12-26)
Microchannels based microfluidic systems are able to obtain monodispersed microparticles but are limited by cost, time and channel clogging. We succeeded in on the fly encapsulation of high ketoprofen contents in acrylate-based copolymer microbeads by environment friendly UV induced free
F Jamali et al.
Clinical pharmacokinetics, 19(3), 197-217 (1990-09-01)
Ketoprofen, a potent nonsteroidal anti-inflammatory drug (NSAID) of the 2-arylpropionic acid class, has been used clinically for over 15 years in Europe, and has recently been introduced in the United States. Although it possesses a chiral centre, with only the