19899
CHAPS 100 mM solution
동의어(들):
CHAPS solution
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C32H58N2O7S
CAS 번호:
Molecular Weight:
614.88
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12161902
MDL number:
InChI
1S/C32H58N2O7S/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41)/t21-,22?,23-,24-,25+,26+,27-,28+,30+,31+,32-/m1/s1
SMILES string
C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)CC4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
InChI key
UMCMPZBLKLEWAF-RFCNGIAKSA-N
description
zwitterionic
form
liquid
mol wt
614.88 g/mol
concentration
100 mM in H2O
technique(s)
protein quantification: suitable
CMC
8 mM
transition temp
cloud point >100 °C
density
1.01 g/mL at 20 °C
storage temp.
2-8°C
Quality Level
General description
3-[(3-cholamidopropyl) dimethylammonio]-1-propanesulfonate (CHAPS) is a biocompatible surfactant. It is a derivative of cholic acid comprising a hydrophobic cholesterol-like skeleton possessing three hydroxyl groups and a zwitterionic aliphatic tail.
Application
CHAPS 100 mM solution has been used as a component of lysis buffer for the extraction of proteins from goat endometrial epithelial cells (EECs) and liver tissue.
Biochem/physiol Actions
3-[(3-cholamidopropyl) dimethylammonio]-1-propanesulfonate (CHAPS) exhibits the properties of both sulfobetaine-type surfactants and bile salts. It is involved in the protein extraction process for proteomic analysis and reconstitution of membrane proteins into lipid vesicles (proteoliposomes). CHAPS is broadly used in biochemistry for membrane protein and receptor isolation and purification. It is conveniently used in pharmaceuticals and medicines due to its biocompatibility, noncharged character, nondenaturing, and disaggregating properties.
저장 등급
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
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