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Merck

21210

D-Pantothenic acid hemicalcium salt

≥98.0%

동의어(들):

(R)-(+)-N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-β-alanine hemicalcium salt, Calcium D-pantothenate, Vitamin B5

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
HOCH2C(CH3)2CH(OH)CONHCH2CH2CO2 ·1/2Ca
CAS 번호:
Molecular Weight:
238.27
NACRES:
NA.79
PubChem Substance ID:
eCl@ss:
34058012
UNSPSC Code:
12352106
EC Number:
205-278-9
MDL number:
Beilstein/REAXYS Number:
3769272
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InChI key

FAPWYRCQGJNNSJ-UBKPKTQASA-L

InChI

1S/2C9H17NO5.Ca/c2*1-9(2,5-11)7(14)8(15)10-4-3-6(12)13;/h2*7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13);/q;;+2/p-2/t2*7-;/m00./s1

SMILES string

CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)O[Ca]OC(=O)CCNC(=O)[C@H](O)C(C)(C)CO

biological source

synthetic

assay

≥98.0%

form

powder or crystals

optical activity

[α]20/D +27±2°, c = 5% in H2O

impurities

≤0.002% heavy metals

loss

≤3% loss on drying

color

white

pH

6.8-7.2 (25 °C, 50 mg/mL in H2O)

solubility

H2O: 50 mg/mL at 25 °C, clear, almost colorless

Quality Level

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General description

D-Pantothenic acid hemicalcium salt, also referred as calcium D-pantothenate, is a water soluble B complex vitamin. It is present in a variety of foods.
Due to the unstable, hygroscopic nature of the free acid, the calcium salt is employed.

Application

D-Pantothenic acid hemicalcium salt has been used as a supplement in complete media to culture Aspergillus-nidulans.
Precursor in the biosynthesis of coenzyme A.

Biochem/physiol Actions

D-Panthenol is the alcohol analog and biological precursor of D-pantothenic acid. These analogs are precursors in the biosynthesis of the phosphopantetheine moiety of coenzyme A. D-Panthenol and D-Pantothenic acid are used in a variety of skin protection products. D-pantothenic acid may have a role in controlling keratinocyte proliferation and differentiation. D-Panthenol may be used for studies of skin protection emulsions from UV irradiation and as a humectant. D-pantothenic acid is crucial for normal epithelial function. It facilitates wound healing process.

저장 등급

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Transport Assays in Aspergillus nidulans
Krypotou E and Diallinas G
Molecular Microbiology (2013)
Pantothenic acid
Kelly GS
Alternative Medicine Review, 16(3), 263-275 (2011)
Pantothenic acid
Rawalpally TR
Kirk-Othmer Encyclopedia of Chemical Technology (2000)
Wound healing activity of Memecylon umbellatum Burm
Puratchikody A and Nagalakshmi G
Journal of plant sciences, 2(2), 179-186 (2007)
Daisaku Kobayashi et al.
Journal of pharmacological sciences, 115(2), 230-234 (2011-01-25)
It has been reported that pantothenic acid (vitamin B5) and panthenol, an alcohol derivative of pantothenic acid, have beneficial moisturizing effects on the skin. However, few studies have investigated the mechanism of action of pantothenic acid on skin tissues. We

문서

Enzyme Reagent Coenzyme A (CoA, CoASH or HSCoA) is the key cofactor in first step of the TCA cycle, responsible for transferring the acetyl group from pyruvate oxidation to oxaloacetate yielding citrate. Available through Sigma-Aldrich online.

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