37291
Dihydroethidium
BioReagent, suitable for fluorescence, ≥95% (HPCE)
동의어(들):
2,7-Diamino-10-ethyl-9-phenyl-9,10-dihydrophenanthridine, 3,8-Diamino-5,6-dihydro-5-ethyl-6-phenylphenanthridine, Hydroethidine
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C21H21N3
CAS 번호:
Molecular Weight:
315.41
UNSPSC Code:
12161505
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5107482
InChI
1S/C21H21N3/c1-2-24-20-13-16(23)9-11-18(20)17-10-8-15(22)12-19(17)21(24)14-6-4-3-5-7-14/h3-13,21H,2,22-23H2,1H3
SMILES string
CCN1C(c2ccccc2)c3cc(N)ccc3-c4ccc(N)cc14
InChI key
XYJODUBPWNZLML-UHFFFAOYSA-N
product line
BioReagent
assay
≥95% (HPCE)
form
solid
Quality Level
mol wt
315.41 g/mol
solubility
acetonitrile: soluble, methanol: soluble
fluorescence
λex 358 nm; λem 461 nm, λex 392 nm; λem 410 nm in methanol
suitability
suitable for fluorescence
storage temp.
−20°C
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Application
Dihydroethidium (dHEt), a fluorescene probe, is used to detect the presence of reactive oxygen species (ROS) such as superoxides.
Redox indicator. Blue fluorescence until oxidized to ethidium.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
B-ring reduced analog of ethidium
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Anna Rita Fetoni et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(9), 4011-4023 (2013-03-01)
This study addresses the relationship between cochlear oxidative damage and auditory cortical injury in a rat model of repeated noise exposure. To test the effect of increased antioxidant defenses, a water-soluble coenzyme Q10 analog (Qter) was used. We analyzed auditory
Francisco R M Laurindo et al.
Methods in enzymology, 441, 237-260 (2008-06-17)
Assessment of low-level superoxide in nonphagocytic cells is crucial for assessing redox-dependent signaling pathways and the role of enzymes such as the NADPH oxidase complex. However, most superoxide probes present inherent limitations. Particularly, assessment of dihydroethidium (DHE) fluorescence is limited
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Dyskeratosis congenita is an inherited disease caused by mutations in genes coding for telomeric components. It was previously reported that expression of a dyskerin-derived peptide, GSE24.2, increases telomerase activity, regulates gene expression and decreases DNA damage and oxidative stress in
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