69037
Ureidosuccinic acid
98.0-102.0% (T)
동의어(들):
N-Carbamoyl-DL-aspartic acid
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
HOOCCH2CH(NHCONH2)COOH
CAS 번호:
Molecular Weight:
176.13
UNSPSC Code:
12352106
NACRES:
NA.25
PubChem Substance ID:
EC Number:
213-096-6
Beilstein/REAXYS Number:
1726861
MDL number:
Quality Segment
assay
98.0-102.0% (T)
mp
~175 °C (dec.)
format
neat
SMILES string
NC(=O)NC(CC(O)=O)C(O)=O
InChI
1S/C5H8N2O5/c6-5(12)7-2(4(10)11)1-3(8)9/h2H,1H2,(H,8,9)(H,10,11)(H3,6,7,12)
InChI key
HLKXYZVTANABHZ-UHFFFAOYSA-N
Biochem/physiol Actions
Metabolite of pyrimidine biosynthesis, alanine, aspartate and glutamate metabolism.
저장 등급
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
L D Fairbanks et al.
Journal of chromatography. B, Biomedical sciences and applications, 732(2), 487-493 (1999-10-12)
Leflunomide is an immunomodulatory drug which acts by inhibiting dihydroorotic acid dehydrogenase, the fourth enzyme of pyrimidine biosynthesis. We modified our high-performance liquid chromatography method to demonstrate that the principal metabolite in mitogen-stimulated human T-lymphocytes incubated with leflunomide was not
André B P van Kuilenburg et al.
Clinical chemistry, 50(11), 2117-2124 (2004-09-18)
The concentrations of the pyrimidine "de novo" metabolites and their degradation products in urine are useful indicators for the diagnosis of an inborn error of the pyrimidine de novo pathway or a urea-cycle defect. Until now, no procedure was available
Amy J Rice et al.
Analytical biochemistry, 441(1), 87-94 (2013-06-19)
Dihydroorotase (DHOase) is the third enzyme in the de novo pyrimidine biosynthesis pathway and is a potential new antibacterial drug target. No target-based high-throughput screening (HTS) assay for this enzyme has been reported to date. Here, we optimized two colorimetric-based