77140
Peptidoglycan from Staphylococcus aureus
cell wall component
동의어(들):
Peptidoglycan from S. aureus
form
lyophilized powder
solubility
soluble, hazy to turbid, colorless to faintly yellow
storage temp.
−20°C
Quality Level
관련 카테고리
Application
Peptidoglycan from Staphylococcus aureus has been used:
- for the stimulation of lymphocytes: peptidoglycan activates the toll-like receptor 2 (TLR2), present in mammalian cells. It works as an antagonist of Poly (I:C)
- for g-type lysozyme stimulation by intraperitoneally inoculating it into sole specimens
- in phosphate buffer saline and injected into Labeo rohita fingerlings, to study its effect on nucleotide-binding oligomerization domain-2 (NOD-2) gene expression
Biochem/physiol Actions
The cell wall of gram positive bacteria is largely made up of peptidoglycan. It is composed of polysaccharide chains interlinked by peptide bridges. This peptidoglycan gives a certain rigidity to the cell wall and gives the cell mechanical strength. It is a surface molecule which is known to stimulate immune reactions including cytokine production to fever.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
Major component of the cell wall in gram positive organisms. Consists of a glycan backbone with alternating β 1-4 linked residues of N-acetyl-D-glucosamine and muramic acid. The immunological activities of bacterial peptidoglycans; Peptidoglycan types of bacterial cell walls and their taxonomic implications; Antibody response to peptidoglycan during staphylococcal infections.
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Xue Kong et al.
Frontiers in physiology, 9, 1476-1476 (2018-11-09)
Vesicomyidae clams are common species living in cold seeps, which incorporates symbiotic bacteria into their body maintaining endosymbiosis relationship. As members of pattern recognition receptor (PRR) family, peptidoglycan recognition proteins (PGRPs) recognize pathogen associated molecular patterns and play an important
Genomic characterization, phylogeny and gene regulation of g-type lysozyme in sole (Solea senegalensis)
Ponce M, et al.
Fish & Shellfish Immunology, 31(6), 925-937 (2011)
The immunological activities of bacterial peptidoglycans.
D E Stewart-Tull
Annual review of microbiology, 34, 311-340 (1980-01-01)
L J Wheat et al.
The Journal of infectious diseases, 147(1), 16-22 (1983-01-01)
Levels of antibodies to peptidoglycan were measured by solid-phase radioimmunoassay in 76 patients with Staphylococcus aureus infections and 44 patients with infections caused by other bacteria. Levels of IgM antibodies to peptidoglycan were elevated in 24% of the patients with
Sara Abouelasrar Salama et al.
Mediators of inflammation, 2020, 6087109-6087109 (2020-07-23)
The serum amyloid A (SAA) gene family is highly conserved and encodes acute phase proteins that are upregulated in response to inflammatory triggers. Over the years, a considerable amount of literature has been published attributing a wide range of biological
문서
Peptidoglycan structure: alternating GlcNAc and N-acetylmuramic acid cross-linked to peptides form the basic backbone.
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