85580
Spermidine trihydrochloride
From microbial,synthetic, ≥99.0% (AT), nNos inhibitor, powder
동의어(들):
N-(3-Aminopropyl)-1,4-butanediamine trihydrochloride
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
NH2(CH2)3NH(CH2)4NH2 · 3HCl
CAS 번호:
Molecular Weight:
254.63
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
206-379-0
MDL number:
Beilstein/REAXYS Number:
3552356
제품 이름
Spermidine trihydrochloride, ≥99.0% (AT)
InChI key
LCNBIHVSOPXFMR-UHFFFAOYSA-N
InChI
1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H
SMILES string
Cl[H].Cl[H].Cl[H].NCCCCNCCCN
biological source
microbial
synthetic
assay
≥99.0% (AT)
form
powder
mp
~250 °C (dec.)
257-259 °C (lit.)
solubility
H2O: 0.1 g/mL, clear, colorless
storage temp.
room temp
Quality Level
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Application
Spermidine trihydrochloride has been used as standard for the detection of biogenic amines using HPLC.
Biochem/physiol Actions
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; Stimulates T4 polynucleotide kinase activity.
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.
Spermidine modulates various cellular activities like cellular development and differentiation, stability of DNA and apoptosis.
Disclaimer
Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.
General description
Spermidine is a polyamine and a trivalent organic cation.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Enzymology Primer for Recombinant DNA Technology, 233-306 (1996)
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문서
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
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