A4477

Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer⁸⁴⁵) antibody produced in rabbit

Name: Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer<SUP>845</SUP>) antibody produced in rabbit
Brand: SIGMA

affinity isolated antibody, buffered aqueous glycerol solution

동의어(들):

Anti-phospho-AMPA Glutamate Receptor 1 (pSer⁸⁴⁵)

조직 및 계약 가격을 보려면 로그인를 클릭합니다.

크기 선택

제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD04040523

Conjugate:

unconjugated

Clone:

polyclonal

Application:

dot blot
western blot

Species reactivity:

human, rat

Citations:

Technique(s):

dot blot: 1:1000
western blot: 1:1,000 using rat brain extracts

Uniprot accession no.:

P42261

주요 문서

모든 문서 보기

기술 서비스

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도움 문의

기술 서비스

도움이 필요하신가요? 저희 숙련된 과학자 팀이 도와드리겠습니다.

도움 문의

제품 이름

Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer⁸⁴⁵) antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

mol wt

antigen 100 kDa

species reactivity

human, rat

technique(s)

dot blot: 1:1000
western blot: 1:1,000 using rat brain extracts

UniProt accession no.

P42261

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer845)

Quality Level

200

Gene Information

human ... GRIA1(2890)
rat ... Gria1(50592)

Application

Rabbit Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer⁸⁴⁵) antibody can be used for western blot analysis at 1:1,000 using rat brain extracts.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

AMPA is a transmembrane receptor for glutamate that regulates synapsis in the central nervous system. It is composed of 4 types of subunits, GluR1, 2, 3, 4.

Rabbit Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer⁸⁴⁵) antibody recognizes human and rat AMPA Receptor, GluR1 subunit (pSer⁸⁴⁵).

Immunogen

synthetic phosphorylated peptide corresponding to a region near serine 845 of rat glutamate receptor subunit GluR1.

Physical form

Solution in 10 mM HEPES buffer, pH 7.5, containing 150 mM NaCl, 100 μg/ml BSA and 50% glycerol.

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당사의 제품 선택기 도구.을(를) 시도해 보세요.

저장 등급

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Amygdala levels of the GluA1 subunit of glutamate receptors and its phosphorylation state at serine 845 in the anterior hippocampus are biomarkers of ictal fear but not anxiety.

Rodrigo Bainy Leal et al.

Molecular psychiatry, 25(3), 655-665 (2018-06-09)

Fear is a conscious state caused by exposure to real or imagined threats that trigger stress responses that affect the body and brain, particularly limbic structures. A sub-group of patients with mesial temporal lobe epilepsy related to hippocampus sclerosis (MTLE-HS)

AMPA Receptor-mTOR Activation is Required for the Antidepressant-Like Effects of Sarcosine during the Forced Swim Test in Rats: Insertion of AMPA Receptor may Play a Role.

Kuang-Ti Chen et al.

Frontiers in behavioral neuroscience, 9, 162-162 (2015-07-08)

Sarcosine, an endogenous amino acid, is a competitive inhibitor of the type I glycine transporter and an N-methyl-d-aspartate receptor (NMDAR) coagonist. Recently, we found that sarcosine, an NMDAR enhancer, can improve depression-related behaviors in rodents and humans. This result differs

LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity.

Loukia Parisiadou et al.

Nature neuroscience, 17(3), 367-376 (2014-01-28)

Leucine-rich repeat kinase 2 (LRRK2) is enriched in the striatal projection neurons (SPNs). We found that LRRK2 negatively regulates protein kinase A (PKA) activity in the SPNs during synaptogenesis and in response to dopamine receptor Drd1 activation. LRRK2 interacted with

A single high dose of dexamethasone affects the phosphorylation state of glutamate AMPA receptors in the human limbic system.

M W Lopes et al.

Translational psychiatry, 6(12), e986-e986 (2016-12-14)

Glucocorticoids (GC) released during stress response exert feedforward effects in the whole brain, but particularly in the limbic circuits that modulates cognition, emotion and behavior. GC are the most commonly prescribed anti-inflammatory and immunosuppressant medication worldwide and pharmacological GC treatment

Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer⁸⁴⁵) antibody produced in rabbit

affinity isolated antibody, buffered aqueous glycerol solution

크기 선택

제품정보 (DICE 배송 시 비용 별도)

주요 문서

속성

제품 이름

biological source

conjugate

antibody form

antibody product type

clone

form

mol wt

species reactivity

technique(s)

UniProt accession no.

shipped in

storage temp.

target post-translational modification

Quality Level

Gene Information

설명

Application

Disclaimer

General description

Immunogen

Physical form

안전성 정보

저장 등급

wgk

flash_point_f

flash_point_c

문서

시험 성적서(COA)

이 제품을 이미 가지고 계십니까?

관련 참고 논문

관련 참고 프로토콜

관련 콘텐츠

기술 서비스

Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer845) antibody produced in rabbit

affinity isolated antibody, buffered aqueous glycerol solution

크기 선택

제품정보 (DICE 배송 시 비용 별도)

주요 문서

속성

제품 이름

biological source

conjugate

antibody form

antibody product type

clone

form

mol wt

species reactivity

technique(s)

UniProt accession no.

shipped in

storage temp.

target post-translational modification

Quality Level

Gene Information

설명

Application

Disclaimer

General description

Immunogen

Physical form

안전성 정보

저장 등급

wgk

flash_point_f

flash_point_c

문서

시험 성적서(COA)

이 제품을 이미 가지고 계십니까?

관련 참고 논문

관련 참고 프로토콜

관련 콘텐츠

기술 서비스

Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer⁸⁴⁵) antibody produced in rabbit