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Merck

A5626

Acetylthiocholine chloride

≥99% (TLC), powder

동의어(들):

(2-Mercaptoethyl)trimethylammonium chloride acetate

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
CH3COSCH2CH2N(CH3)3Cl
CAS 번호:
Molecular Weight:
197.73
NACRES:
NA.83
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
227-953-7
MDL number:
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Quality Level

assay

≥99% (TLC)

form

powder

solubility

water: 100 mg/mL, clear to slightly hazy, colorless

storage temp.

−20°C

SMILES string

[Cl-].CC(=O)SCC[N+](C)(C)C

InChI

1S/C7H16NOS.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1

InChI key

GZYVLKKMMDFCKR-UHFFFAOYSA-M

Gene Information

human ... ACHE(43)

Application

Acetylthiocholine chloride has been used to determine the acetylcholine esterase activity of semen exosomes (SE). It has also been used as a substrate for acetylcholine esterase in microcalorimetric study of its kinetic parameters.

Biochem/physiol Actions

Acetylcholinesterase substrate and nicotinic acetylcholine receptor agonist.
Acetylcholinesterase (AChE) enzyme plays an important physiological role in the neurotransmission process.

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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문서 라이브러리 방문

Tanja Botić et al.
European journal of medicinal chemistry, 136, 294-304 (2017-05-16)
The brominated pyrroloiminoquinone alkaloids discorhabdins B, L and G and 3-dihydro-7,8- dehydrodiscorhabdin C, isolated from methanol extracts of two specimens of Latrunculia sp. sponges collected near the Antarctic Peninsula, are here demonstrated for the first time to be reversible competitive
Isolation of Exosomes from Semen for in vitro Uptake and HIV-1 Infection Assays
Madison MN, et al.
Bio-protocol, 7(7) (2017)
Jerneja Kladnik et al.
International journal of molecular sciences, 21(16) (2020-08-13)
The increasing number of Alzheimer's disease (AD) cases requires the development of new improved drug candidates, possessing the ability of more efficient treatment as well as less unwanted side effects. Cholinesterase enzymes are highly associated with the development of AD
Livia F Sgobbi et al.
Biosensors & bioelectronics, 100, 290-297 (2017-09-25)
A plethora of publications has continuously reported electrochemical biosensors for detection of pesticides. However, those devices rarely accomplish commercial application due to technical issues associated with the lack of stability and high cost of the biological recognition element (enzyme). Alternatively
Muhammad Shakil Shah et al.
Computational biology and chemistry, 76, 310-317 (2018-08-25)
Cholinesterases (ChEs) play a vital role in regulating cholinergic transmission. Inhibition of ChEs is thought to be an emerging and useful therapeutic target for neurodegenerative disorders through restoration of acetylcholine (ACh) levels in the brain (e.g. Alzheimer's disease). To increase

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