A5971
Anti-Water Channel Aquaporin 4 antibody produced in rabbit
lyophilized powder, affinity isolated antibody
동의어(들):
Anti-AQP4, Anti-Mercurial-Insensitive Water Channel, Anti-WCH4
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크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
Conjugate:
unconjugated
Clone:
polyclonal
Application:
FACS, ICC, IHC, WB
Citations:
70
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
human, mouse, rat
technique(s)
flow cytometry: suitable (indirect), immunocytochemistry: suitable, immunohistochemistry: suitable, western blot: suitable
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... AQP4(361)
mouse ... Aqp4(11829)
rat ... Aqp4(25293)
General description
AQP4 is an osmoreceptor that regulates water flow in the CNS. It is abundant in astrocytes, but is also weakly noticeable in pulmonary, intestinal, ocular and renal tissues. Rabbit Anti-Water Channel Aquaporin 4 antibody recognizes aquaporin 4 in human, mice and rats.
Immunogen
recombinant fusion protein corresponding to residues 249-323 of rat AQP4 fused to GST.
Application
Rabbit Anti-Water Channel Aquaporin 4 antibody can be used for immunohistochemical applications. The antibody can also be used for immunocytochemistry, western blot and flow cytometry applications.
Biochem/physiol Actions
Immunoprecipation and western blot analysis using HEK-293 cells that had been transfected with GFP-AQP4 was performed using rabbit anti-AQP4 as the primary antibody at 2μl/ml.
Physical form
Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, and 0.05% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
관련 콘텐츠
Instructions
Paraneoplastic Neuromyelitis Optica Associated with Lung Adenocarcinoma in a Young Woman.
Kyoung Won Baik et al.
Journal of clinical neurology (Seoul, Korea), 14(2), 246-247 (2018-04-10)
Gry Fluge Vindedal et al.
Molecular and cellular neurosciences, 77, 47-52 (2016-11-05)
There is a constitutive production of water in brain. The efflux routes of this excess water remain to be identified. We used basal brain water content as a proxy for the capacity of water exit routes. Basal brain water content
Michelle Figueroa et al.
JAMA neurology, 71(4), 495-498 (2014-04-16)
Reports of neuromyelitis optica spectrum disorder (NMOSD) occurring in the setting of neoplasia suggest that aquaporin-4 autoimmunity may in some cases have a paraneoplastic basis. In this case report, we describe a patient with NMOSD whose test results were seropositive