A6419
Adenosine 5′-triphosphate disodium salt hydrate
microbial, BioReagent, suitable for cell culture, ≥99% (HPLC)
동의어(들):
ATP disodium salt
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C10H14N5Na2O13P3 · xH2O
CAS 번호:
Molecular Weight:
551.14 (anhydrous basis)
UNSPSC Code:
12352207
eCl@ss:
32160414
PubChem Substance ID:
NACRES:
NA.75
MDL number:
Assay:
≥99% (HPLC)
Form:
powder
SMILES string
O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O
InChI
1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
InChI key
NTBQNWBHIXNPRU-MSQVLRTGSA-L
biological source
microbial
product line
BioReagent
assay
≥99% (HPLC)
form
powder
technique(s)
cell culture | mammalian: suitable
solubility
H2O: 50 mg/mL
storage temp.
−20°C
Quality Level
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General description
Adenosine 5′-triphosphate (ATP) is essential for biological processes including neurotransmission, signal transduction, muscle contraction and cardiac function. ATP is the major energy potential for living systems. They are released from cells under stress and play a key role in immune response. ATP release from injured neurons and consequent breakdown leads to generation of adenosine. ATP may serve as a therapeutic option in anaesthesia and intensive care medicine for the management of pain. Elevated ATP levels are indicative of cell damage and inflammation.
Application
Adenosine 5′-triphosphate disodium salt hydrate has been used:
- as a component of transfection mix for the transformation of CRISPR/Cas9 plasmid in parasites
- in inflammasome activation assays in bone marrow derived macrophages
- for the stimulation of macrophages
- in nucleotide synthesis
Biochem/physiol Actions
P2 purinergic agonist; increases activity of Ca2+-activated K+ channels; substrate for ATP-dependent enzyme systems
P2 purinocepter agonist.
저장 등급
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type N95 (US)
Deuterated nucleotides as chemical probes of RNA structure: a detailed protocol for the enzymatic synthesis of a complete set of nucleotides specifically deuterated at ribose carbons
Tullius T, et al.
ScienceOpen Research (2018)
Effect of interleukin-31 on septic shock through regulating inflammasomes and interleukin-1beta
Gu X, et al.
Experimental and Therapeutic Medicine, 16(1), 171-177 (2018)
Potential value of adenosine 5?-triphosphate (ATP) and adenosine in anaesthesia and intensive care medicine
Skrabanja ATP, et al.
British Journal of Anaesthesia, 94(5), 556-562 (2005)
Adenosine and its receptors as therapeutic targets: an overview
Sachdeva S and Gupta M
Saudi Pharmaceutical Journal : SPJ : The Official Publication of the Saudi Pharmaceutical Society, 21(3), 245-253 (2013)
Conditional knockdown of proteins using auxin-inducible degron (AID) fusions in Toxoplasma gondii
Brown KM, et al.
Bio-protocol, 8(4), 245-253 (2018)
관련 콘텐츠
Product Information Sheet
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