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Merck

A6559

Adenosine 5′-triphosphate disodium salt solution

≥95% (HPLC), liquid

동의어(들):

ATP

조직 및 계약 가격을 보려면 로그인를 클릭합니다.

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제품정보 (DICE 배송 시 비용 별도)

CAS 번호:
UNSPSC Code:
41106305
eCl@ss:
32160414
PubChem Substance ID:
NACRES:
NA.52
MDL number:
Assay:
≥95%
Biological source:
yeast
Form:
liquid
Storage temp.:
−20°C
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제품 이름

Adenosine 5′-triphosphate disodium salt solution, Crystalline ATP, HPLC purified, aqueous solution for RNA transcription

SMILES string

[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O

InChI

1S/C10H16N5O13P3.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1

InChI key

TTWYZDPBDWHJOR-IDIVVRGQSA-L

biological source

yeast

assay

≥95%

form

liquid

concentration

100 mM in H2O (adjusted to pH 7 with Trizma®
base)

foreign activity

DNase, RNase, none detected

shipped in

dry ice

storage temp.

−20°C

Quality Level

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General description

Adenosine 5′-triphosphate disodium salt solution is suitable for use in molecular biology applications such as kinase reactions or DNA-dependent RNA polymerase transcription.

Application

Adenosine 5′-triphosphate disodium salt solution has been used:
  • as a standard to evaluate the extracellular ATP release from marginal cells of stria vascular
  • as a component of the internal pipette solution to establish a recording electrode to study neurite stretching
  • in in vitro VPS34 (catalytic subunit of the phosphatidylinositol 3-kinase (PtdIns3K) complex) activity assay
  • as a component of lysis and resealing buffers for ATP studies
  • in spectrophotometric measurement of H+ transport in fluorescein isothiocyanate (FITC)-dextran loaded A549 (adenocarcinomic human alveolar basal epithelial cells) and HeLa cells
  • to induce pyroptosis in lipopolysaccharide treated fibroblast-like synoviocytes (FLSs)

Biochem/physiol Actions

Adenosine 5′-triphosphate (ATP) is an important energy currency in all living organisms. It possesses high phosphate transfer potential. ATP is involved in several biological processes such as membrane transport, muscle contraction and synthesis, and degradation of biological molecules. It plays a role as an intracellular and extracellular signaling molecule in certain cellular processes such as cell motility, organ development, neurotransmission, and insulin secretion.

Legal Information

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

저장 등급

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Yahui Huang et al.
Archiv der Pharmazie (2018-06-29)
Inhibition of spleen tyrosine kinase (Syk) is a promising strategy for the treatment of various allergic and autoimmune disorders such as asthma, rheumatoid arthritis, and allergic rhinitis. Previously, a Syk inhibitor with novel indazole scaffold was discovered by structure-based virtual
James Franklin Tucker et al.
PLoS genetics, 12(2), e1005873-e1005873 (2016-02-20)
Epigenetic gene silencing plays a critical role in regulating gene expression and contributes to organismal development and cell fate acquisition in eukaryotes. In fission yeast, Schizosaccharomyces pombe, heterochromatin-associated gene silencing is known to be mediated by RNA processing pathways including
Cooper GM
The Cell: A Molecular Approach (2000)
Identification of small molecule inhibitors of phosphatidylinositol 3-kinase and autophagy.
Farkas T
The Journal of Biological Chemistry, 286(45), 38904-38912 (2011)
DRAM1 regulates autophagy flux through lysosomes.
Zhang XD
PLoS ONE, 8(5), e63245-e63245 (2013)

문서

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관련 콘텐츠

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Product Information Sheet

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