A7699

Adenosine 5′-triphosphate disodium salt hydrate

Name: Adenosine 5′-triphosphate disodium salt hydrate
Brand: SIGMA

BioXtra, ≥99% (HPLC), from microbial

동의어(들):

ATP disodium salt

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):

C₁₀H₁₄N₅Na₂O₁₃P₃ · xH₂O

CAS 번호:

34369-07-8

Molecular Weight:

551.14 (anhydrous basis)

PubChem Substance ID:

24891270

eCl@ss:

32160414

UNSPSC Code:

41106305

NACRES:

NA.51

EC Number:

213-579-1

MDL number:

MFCD00150755

주요 문서

모든 문서 보기

기술 서비스

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도움 문의

기술 서비스

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도움 문의

제품 이름

Adenosine 5′-triphosphate disodium salt hydrate, BioXtra, ≥99% (HPLC), from microbial

InChI key

NTBQNWBHIXNPRU-MSQVLRTGSA-L

InChI

1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1

SMILES string

O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O

biological source

microbial

product line

BioXtra

assay

≥99% (HPLC)

form

powder

Quality Level

300

mol wt

551.14 g/mol

impurities

≤0.1% inorganic P
≤3% solvent content

color

white

pKa

(1) 4.0, (2) 6.5

solubility

H₂O: 50 mg/mL, clear, colorless

anion traces

chloride (Cl^-): ≤0.05%

cation traces

Al: ≤0.005%
Ca: ≤0.01%
Cu: ≤0.001%
Fe: ≤0.05%
K: ≤0.01%
Mg: ≤0.005%
NH₄⁺: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

λ_max

259 nm

fluorescence

λ_em 15.4 in 0.1 M phosphate pH 7.0

storage temp.

−20°C

유사한 제품을 찾으십니까? 방문 제품 비교 안내

Application

Adenosine 5γ-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is use in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. ATP serves as a coenzyme in a wide array of enzymatic reactions.

Biochem/physiol Actions

P₂ purinergic agonist; increases activity of Ca²⁺-activated K⁺ channels; substrate for ATP-dependent enzyme systems

P₂ purinocepter agonist.

저장 등급

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type N95 (US)

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시험 성적서(COA)

Lot/Batch Number

0000523976

0000506528

0000506540

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Local release of ATP into the arterial inflow and venous drainage of human skeletal muscle: insight from ATP determination with the intravascular microdialysis technique.

Stefan P Mortensen et al.

The Journal of physiology, 589(Pt 7), 1847-1857 (2011-02-09)

Intraluminal ATP could play an important role in the local regulation of skeletal muscle blood flow, but the stimuli that cause ATP release and the levels of plasma ATP in vessels supplying and draining human skeletal muscle remain unclear. To

Adenine nucleotide control of coronary blood flow during exercise.

Mark W Gorman et al.

American journal of physiology. Heart and circulatory physiology, 299(6), H1981-H1989 (2010-09-21)

The adenine nucleotide hypothesis postulates that the ATP released from red blood cells is broken down to ADP and AMP in coronary capillaries and that ATP, ADP, and AMP act on purinergic receptors on the surface of capillary endothelial cells.

Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation.

Shaima'a Hamarsheh et al.

Nature communications, 11(1), 1659-1659 (2020-04-05)

Oncogenic Ras mutations occur in various leukemias. It was unclear if, besides the direct transforming effect via constant RAS/MEK/ERK signaling, an inflammation-related effect of KRAS contributes to the disease. Here, we identify a functional link between oncogenic KrasG12D and NLRP3

MARK4 (Microtubule Affinity-Regulating Kinase 4)-Dependent Inflammasome Activation Promotes Atherosclerosis-Brief Report.

Marc Clement et al.

Arteriosclerosis, thrombosis, and vascular biology, 39(8), 1645-1651 (2019-06-07)

MARK4 (microtubule affinity-regulating kinase 4) regulates NLRP3 (nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin domain containing 3) inflammasome activation. The aim of the study is to examine the role of MARK4 in hematopoietic cells during atherosclerosis. We show increased MARK4

Dielectric spectra broadening as a signature for dipole-matrix interaction. III. Water in adenosine monophosphate/adenosine-5'-triphosphate solutions.

Alexander Puzenko et al.

The Journal of chemical physics, 137(19), 194502-194502 (2012-11-28)

In this, the third part of our series on the dielectric spectrum symmetrical broadening of water, we consider the nucleotide aqueous solutions. Where in Parts I [E. Levy et al., J. Chem. Phys. 136, 114502 (2012)] and II [E. Levy

모든 관련된 서류 보기

프로토콜

LC/MS Analysis of Nucleotides on SeQuant ZIC-cHILIC

HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.

LC/MS Analysis of Nucleotides SeQuant^® ZIC^®-cHILIC – Effect of pH

ZIC^®-cHILIC is a densely bonded zwitterionic stationary phase with phosphorylcholine functional groups covalently attached to silica.

Adenosine 5′-triphosphate disodium salt hydrate

BioXtra, ≥99% (HPLC), from microbial

크기 선택

제품정보 (DICE 배송 시 비용 별도)

주요 문서

속성

제품 이름

InChI key

InChI

SMILES string

biological source

product line

assay

form

Quality Level

mol wt

impurities

color

pKa

solubility

anion traces

cation traces

λmax

fluorescence

storage temp.

관련 카테고리

설명

Application

Biochem/physiol Actions

안전성 정보

저장 등급

wgk

flash_point_f

flash_point_c

ppe

문서

시험 성적서(COA)

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기술 서비스

λ_max