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Merck

B9285

5-Bromo-2′-deoxyuridine

≥99%, synthetic (organic), powder

동의어(들):

5-BrdU, 5-Bromo-1-(2-deoxy-β-D-ribofuranosyl)uracil, 5-Bromouracil deoxyriboside, BUdR

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C9H11BrN2O5
CAS 번호:
59-14-3
Molecular Weight:
307.10
NACRES:
NA.51
PubChem Substance ID:
24892132
UNSPSC Code:
41106305
EC Number:
200-415-9
MDL number:
MFCD00006529
Beilstein/REAXYS Number:
30395
Assay:
≥99%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
NH4OH: 0.1 M at 20 °C, clear, colorless
Storage temp.:
−20°C

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제품 이름

5-Bromo-2′-deoxyuridine, BioUltra, ≥99%

InChI key

WOVKYSAHUYNSMH-RRKCRQDMSA-N

InChI

1S/C9H11BrN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1

SMILES string

OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(Br)C(=O)NC2=O

biological source

synthetic (organic)

product line

BioUltra

assay

≥99%

form

powder

impurities

≤0.005% Phosphorus (P)
≤0.1% Insoluble matter

ign. residue

≤0.1%

mp

191-194 °C (dec.) (lit.)

solubility

NH4OH: 0.1 M at 20 °C, clear, colorless

cation traces

Al: ≤0.0005%
Ca: ≤0.01%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

storage temp.

−20°C

Quality Level

200

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관련 카테고리

Application

5-Bromo-2′-deoxyuridine has been used:
  • to label proliferating cells in pregnant mice in cell proliferation assay
  • to study the time course of cell proliferation at various times following ischemia, to confirm re-entry of MKI67+ cells in cell cycle to germ cells
  • in 5′-Bromo-2′Deoxyuridine (BrdUrd) staining of fibroblasts

Biochem/physiol Actions

5′-Bromo-2-deoxyuridine (BrdU) staining is predominantly used to observe the multiplication of tumor cells and other tissues in vivo.
5-Bromo-2′-deoxyuridine (5-BrdU) is a thymidine analogue which is incorporated into DNA. 5-BrdU is routinely and extensively used to measure DNA synthesis and to label dividing cells. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.
Thymidine analog used as a mutagen in genetic research. Selectively incorporated into cellular DNA during S-phase.

General description

5′-Bromo-2-deoxyuridine (BrdU) is a carcinogen that may be absorbed by skin or inhalation. BrdU solutions are sensitive to light.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

pictograms

Health hazard
GHS08

signalword

Danger

Hazard Classifications

Muta. 1B - Repr. 2

저장 등급

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

ppe

Eyeshields, Gloves, type N95 (US)

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시험 성적서(COA)

Lot/Batch Number
HMBK8086
HMBK5068
HMBK2172
HMBJ9646
HMBJ5521

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