콘텐츠로 건너뛰기
Merck

C1254

Sodium cholate hydrate

from bovine and/or ovine bile, ≥99%

동의어(들):

3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt, Cholalic acid sodium salt

조직 및 계약 가격을 보려면 로그인를 클릭합니다.

크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C24H39NaO5 · xH2O
CAS 번호:
206986-87-0
Molecular Weight:
430.55 (anhydrous basis)
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
24892390
EC Number:
206-643-5
Beilstein/REAXYS Number:
3582354
MDL number:
MFCD00150749

주요 문서

모든 문서 보기
기술 서비스
도움이 필요하신가요? 저희 숙련된 과학자 팀이 도와드리겠습니다.
도움 문의
기술 서비스
도움이 필요하신가요? 저희 숙련된 과학자 팀이 도와드리겠습니다.
도움 문의

Quality Level

200

InChI key

MUVVIYFKOVLQHL-RCVKHMDESA-M

InChI

1S/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1

SMILES string

O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C

biological source

bovine and/or ovine bile

description

anionic

assay

≥99%

form

powder

mol wt

micellar avg mol wt 900-1300

aggregation number

2-3

technique(s)

DNA purification: suitable, RNA purification: suitable, western blot: suitable

CMC

9-15 mM (20-25°C)

solubility

water: 100 mg/mL, clear, colorless to light yellow

HLB

18

유사한 제품을 찾으십니까? 방문 제품 비교 안내

관련 카테고리

General description

Sodium cholate hydrate, a non-denaturing anionic detergent, plays a crucial role in biochemical research, particularly in protein solubilization and membrane permeabilization, making it essential for protein extraction and purification, especially when dealing with membrane proteins and protein complexes. Derived from cholic acid, a prevalent human bile acid, sodium cholate hydrate′s water solubility and its applications extend to investigating the effects of various substances on cell cultures, making it a versatile tool in laboratory research.

Application

Sodium cholate hydrate has been used in a study to assess the effect of phospholipid formulation and surfactants on the dermal delivery of hydrophilic drugs from elastic liposomes. It has also been used in a study to investigate the elastic deformable vesicles, transfersomes, for transdermal drug delivery.

Biochem/physiol Actions

Bile Salt

Features and Benefits

  • Suitable for Western blotting
  • Suitable for DNA and RNA purification
  • High purity product for research applications

Other Notes

For additional information on our range of Biochemicals, please complete this form.

hcodes

H412

Hazard Classifications

Aquatic Chronic 3

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
0000538066
0000538067
0000534013
0000538066
0000524776

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Li Lei et al.
Current protocols in protein science, 84, 29-29 (2016-04-03)
Fish and human cytochrome P450 (P450) 17A1 catalyze both steroid 17α-hydroxylation and 17α,20-lyase reactions. Fish P450 17A2 catalyzes only 17α-hydroxylation. Both enzymes are microsomal-type P450s, integral membrane proteins that bind to the membrane through their N-terminal hydrophobic segment, the signal
Kevin B Ita et al.
The Journal of pharmacy and pharmacology, 59(9), 1215-1222 (2007-09-22)
The effect of phospholipid formulation and choice of surfactant on skin permeation of selected hydrophilic drugs from elastic liposomes across human epidermal membrane has been studied. Sodium cholate and various concentrations of phosphatidylcholine were used for the preparation of liposomes
Ching-Wei Lin et al.
Nature communications, 10(1), 2874-2874 (2019-06-30)
Covalent doping of single-walled carbon nanotubes (SWCNTs) can modify their optical properties, enabling applications as single-photon emitters and bio-imaging agents. We report here a simple, quick, and controllable method for preparing oxygen-doped SWCNTs with desirable emission spectra. Aqueous nanotube dispersions
Transfersomes for transdermal drug delivery
Benson, H.
Expert Opinion on Drug Delivery, 3, 727-727 (2005)
Yan Qiao et al.
Langmuir : the ACS journal of surfaces and colloids, 27(17), 11090-11097 (2011-07-19)
We report a facile method to synthesize water-soluble gold nanoparticles (AuNPs) using a biosurfactant sodium cholate as reducing reagents and protective groups in aqueous solution at ambient temperature. The diameters (13-70 nm) of uniform AuNPs can be readily adjusted by
모든 관련된 서류 보기

문서

Nanodisc Technology: A Revolutionary System for Study of Membrane Proteins

Read our article about how the Nanodisc system allows for structural studies of membrane proteins.

Probiotics and Human Health

Probiotics exhibit an inhibitory effect on pathogens, help prevent chronic intestinal inflammatory diseases or atopic syndromes, and support the immune system.

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.