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Merck

C141

CGS-21680 hydrochloride hydrate

≥98% (HPLC), Adenosine A2A receptor agonist, solid

동의어(들):

2-p-(2-Carboxyethyl)phenethylamino-5′-N-ethylcarboxamidoadenosine hydrochloride hydrate

조직 및 계약 가격을 보려면 로그인를 클릭합니다.

크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C23H29N7O6 · HCl · xH2O
CAS 번호:
124182-57-6
Molecular Weight:
535.98 (anhydrous basis)
UNSPSC Code:
12352200
PubChem Substance ID:
24277698
NACRES:
NA.77
MDL number:
MFCD11045878
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
100
Storage condition:
desiccated

주요 문서

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제품 이름

CGS-21680 hydrochloride hydrate, solid

SMILES string

O.Cl.CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)nc(NCCc4ccc(CCC(O)=O)cc4)nc23

InChI

1S/C23H29N7O6.ClH.H2O/c1-2-25-21(35)18-16(33)17(34)22(36-18)30-11-27-15-19(24)28-23(29-20(15)30)26-10-9-13-5-3-12(4-6-13)7-8-14(31)32;;/h3-6,11,16-18,22,33-34H,2,7-10H2,1H3,(H,25,35)(H,31,32)(H3,24,26,28,29);1H;1H2/t16-,17+,18-,22+;;/m0../s1

InChI key

VIRPCGAECNOLOO-VBQNEDDFSA-N

assay

≥98% (HPLC)

form

solid

storage condition

desiccated

color

white

solubility

DMSO: >10 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 20 mg/mL

storage temp.

−20°C

Quality Level

100

Gene Information

human ... ADORA2A(135), ADORA2B(136)

관련 카테고리

Biochem/physiol Actions

Adenosine receptor agonist, which possesses selectivity for A2 verses A1 receptors.

Disclaimer

Hygroscopic

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
0000161112
0000156800
0000148795
0000148794
0000148795

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

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N Levens et al.
The Journal of pharmacology and experimental therapeutics, 257(3), 1005-1012 (1991-06-01)
This study compares the renal actions of the A2 selective adenosine agonist, CGS 21680A, with the A1 selective adenosine agonist, N6-cyclopentyladenosine (CPA), and the nonselective agonist, 5'-N-ethylcarboxamide adenosine (NECA), in the anesthetized dog. Initial receptor binding studies in dog brain
M F Jarvis et al.
The Journal of pharmacology and experimental therapeutics, 251(3), 888-893 (1989-12-01)
Characterization of the adenosine A2 receptor has been limited due to the lack of available ligands which have high affinity and selectivity for this adenosine receptor subtype. In the present study, the binding of a highly A2-selective agonist radioligand, [3H]CGS
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