C1506
Cytidine 5′-triphosphate disodium salt
≥95%, P2X4 purinergic receptor agonist, powder
동의어(들):
CTP
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C9H14N3Na2O14P3
CAS 번호:
Molecular Weight:
527.12
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
252-849-3
MDL number:
제품 이름
Cytidine 5′-triphosphate disodium salt, ≥95%
InChI key
NFQMDTRPCFJJND-WFIJOQBCSA-L
InChI
1S/C9H16N3O14P3.2Na/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18);;/q;2*+1/p-2/t4-,6-,7-,8-;;/m1../s1
SMILES string
[Na+].[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O
assay
≥95%
form
powder
storage temp.
−20°C
Quality Level
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General description
Cytidine 5′-triphosphate is a nucleoside triphosphate with a pyrimidine ring. It is present in RNA.
Application
Cytidine 5′-triphosphate disodium salt has been used:
- for the conversion of adenosine monophosphate (AMP) to adenosine diphosphate (ADP) in luminometry analysis
- in the preparation of ribonucleotide 5′-triphosphate precursors stocks for large-scale RNA synthesis
- to perform in vitro transcription
Biochem/physiol Actions
Cytidine 5′-triphosphate (CTP) prevents the action of aspartate carbamoyltransferase. This enzyme participates in pyrimidine biosynthesis. Like adenosine triphosphate (ATP), CTP serves as a molecule of high energy. It acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation.
P2X4 purinergic receptor agonist.
Features and Benefits
This compound is featured on the P2 Receptors: P2X Ion Channel Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)
Secretion From Dense Granules
Platelets and megakaryocytes, 83-93 (2004)
Genetics (2016)
Methods in Molecular Biology, 89-89 (2018)
Sean A McKenna et al.
Nature protocols, 2(12), 3270-3277 (2007-12-15)
RNA synthesis using in vitro transcription by phage T7 RNA polymerase allows preparation of milligram quantities of RNA for biochemical, biophysical and structural investigations. Previous purification approaches relied on gel electrophoretic or gravity-flow chromatography methods. We present here a protocol
Scientific and Technical Terms in Bioengineering and Biological Engineering (2018)
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