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Merck

C3506

Cytosine

≥99%, synthetic (organic), powder

동의어(들):

4-Amino-2-hydroxypyrimidine, 4-Aminopyrimidin-2-(1H)-one

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C4H5N3O
CAS 번호:
Molecular Weight:
111.10
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
200-749-5
MDL number:
Beilstein/REAXYS Number:
2637
Assay:
≥99%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
0.5 M HCl: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow
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제품 이름

Cytosine, ≥99%

InChI

1S/C4H5N3O/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8)

InChI key

OPTASPLRGRRNAP-UHFFFAOYSA-N

SMILES string

NC1=NC(=O)NC=C1

biological source

synthetic (organic)

assay

≥99%

form

powder

mp

>300 °C (lit.)

solubility

0.5 M HCl: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

Quality Level

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Application

Cytosine has been used:
  • for the preparation of nucleobase solutions
  • as a standard for high-performance liquid chromatography (HPLC)
  • for the estimation of global methylation rate
  • for nucleoside 5′-triphosphate (NTP) synthesis
  • purification

Biochem/physiol Actions

Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA).
Cytosine is a pyrimidine, which forms three hydrogen bonds to base pair with guanine. It forms a nucleotide cytidine, that is phosphorylated to cytidine 5′ monophosphate (CMP), cytidine 5′ diphosphate (CDP) and cytidine 5′ triphosphate (CTP).

저장 등급

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Deuterated nucleotides as chemical probes of RNA structure: a detailed protocol for the enzymatic synthesis of a complete set of nucleotides specifically deuterated at ribose carbons
Azad R, et al.
ScienceOpen Research (2015)
Encyclopedia of Genetics (2001)
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Almohammed S, et al.
Sensing and Bio-Sensing Research, 24, 100287-100287 (2019)
Akira Ono et al.
Chemical Society reviews, 40(12), 5855-5866 (2011-08-10)
Pyrimidine base pairs in DNA duplexes selectively capture metal ions to form metal ion-mediated base pairs, which can be evaluated by thermal denaturation, isothermal titration calorimetry, and nuclear magnetic resonance spectroscopy. In this critical review, we discuss the metal ion
Irene M Kaplow et al.
Genome research, 25(6), 907-917 (2015-04-26)
DNA methylation is an epigenetic modification that plays a key role in gene regulation. Previous studies have investigated its genetic basis by mapping genetic variants that are associated with DNA methylation at specific sites, but these have been limited to

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A shortened review of fundamentals of Porous Graphitic Carbon (PGC) materials. What they are and how do they work as a stationary phase material in HPLC?.

다공성 흑연탄소(PGC) 재료의 기본 원리에 대한 간략한 검토. 그것들은 무엇이며, HPLC에서 고정상 재료로 어떻게 작용하는가?

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