C5135
Castor Oil, Ethoxylated
pH range 6.0-8.0
동의어(들):
Cremophor® EL, EL, Macrogolglycerol ricinoleate, PEG-35 castor oil, Polyoxyl-35 castor oil
제품 이름
Castor Oil, Ethoxylated, pH range 6.0-8.0
SMILES string
ClCC(OC(=O)N)CCl
InChI
1S/C4H7Cl2NO2/c5-1-3(2-6)9-4(7)8/h3H,1-2H2,(H2,7,8)
InChI key
JMNCUXPHXKHBPY-UHFFFAOYSA-N
description
non-ionic
form
liquid
mol wt
~2500 g/mol
pH range
6.0-8.0
HLB
12 - 14
application(s)
sample preservation
Quality Level
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Application
Castor Oil, Ethoxylated has been used as a detergent to improve the solubility of dye and to increase the transmembrane permeation. It has been used as a vehicle for drug/stimulant delivery in cells.
Biochem/physiol Actions
Castor Oil, Ethoxylated is used in lipid-based formulations for drugs and solubilization of cosmetics. Castor Oil, Ethoxylated is suitable for the production of semi-solid and liquid formulations of water-insoluble actives and other hydrophobic compounds. Due to its emulsification functionality, it finds application in biological membrane- based drug transport studies.
General description
Castor Oil, Ethoxylated is a nonionic solubilizer and emulsifier made by reacting castor oil with ethylene oxide. It is a pale yellow oily liquid that is clear at temperatures above 26°C. It has a faint but characteristic odour.
Castor Oil, Ethoxylated is polyethylene oxide surfactant and is viscous in nature. It has a hydrophobic-lipophilic balance value in the range of 12-14.
Other Notes
A derivative of castor oil and ethylene oxide.
Legal Information
Cremophor is a registered trademark of BASF SE
저장 등급
10 - Combustible liquids
wgk
WGK 1
flash_point_f
494.6 °F - Not applicable
flash_point_c
257 °C - Not applicable
ppe
Eyeshields, Gloves
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Adrenocortical carcinoma (ACC) is a rare cancer with poor prognosis. Pan-genomic analyses identified p53/Rb and WNT/β-catenin signaling pathways as main contributors to the disease. However, isolated β-catenin constitutive activation failed to induce malignant progression in mouse adrenocortical tumors. Therefore, there
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