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Merck

C6594

Monoclonal Anti-c-Myc−Cy3 antibody produced in mouse

clone 9E10, purified immunoglobulin, buffered aqueous solution

동의어(들):

Anti-c-Myc

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제품정보 (DICE 배송 시 비용 별도)

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
CY3 conjugate
Clone:
9E10, monoclonal
Application:
direct immunofluorescence
Species reactivity:
human
Citations:
24
Technique(s):
direct immunofluorescence: 1:50 using formalin-fixed, paraffin-embedded human colon carcinoma tissue
Uniprot accession no.:
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제품 이름

Monoclonal Anti-c-Myc−Cy3 antibody produced in mouse, clone 9E10, purified immunoglobulin, buffered aqueous solution

biological source

mouse

conjugate

CY3 conjugate

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

9E10, monoclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

direct immunofluorescence: 1:50 using formalin-fixed, paraffin-embedded human colon carcinoma tissue

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... MYC(4609)

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Application

Monoclonal Anti-c-MycCy3 antibody produced in mouse has been used in:
  • western blotting
  • immunocytochemistry
  • Immunofluorescence

Biochem/physiol Actions

The encoded protein is involved in cell proliferation, growth and apoptosis. The c-myc gene has been implicated in the development of a number of neoplasms in a variety of avian and mammalian species. The human c-myc protooncogene is the cellular homolog of the avian v-myc gene found in several leukemogenic retroviruses. Increased expression of the cellular oncogene c-myc has been described in a variety of human tumors, occurring by several different mechanisms, including gene amplification and chromosomal translocation.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Monoclonal Anti-c-myc (mouse IgG1 isotype) is derived from the 9E10 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized BALB/c mouse. The c-Myc gene encodes a polypeptide with a predicted molecular weight of 49 kDa.

Immunogen

synthetic peptide of the human p62c-Myc protein.

Physical form

Solution in 0.01 M sodium phosphate buffered saline containing 1% bovine serum albumin and 15 mM sodium azide.

Legal Information

Cy3 is a trademark of Cytiva

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저장 등급

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Correlation of mutant menin stability with clinical expression of multiple endocrine neoplasia type 1 and its incomplete forms
Shimazu S, et al.
Cancer Science, 102(11), 2097-2102 (2011)
Joe DeBartolo et al.
PLoS computational biology, 10(6), e1003693-e1003693 (2014-06-27)
Programmed cell death is regulated by interactions between pro-apoptotic and prosurvival members of the Bcl-2 family. Pro-apoptotic family members contain a weakly conserved BH3 motif that can adopt an alpha-helical structure and bind to a groove on prosurvival partners Bcl-xL
Human MAMLD1 gene variations seem not sufficient to explain a 46, XY DSD phenotype
Camats N, et al.
PLoS ONE, 10(11), e0142831-e0142831 (2015)
Marie Pierron et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(24), 6525-6537 (2016-06-17)
Diffuse extrasynaptic neurotransmitter receptors constitute an abundant pool of receptors that can be recruited to modulate synaptic strength. Whether the diffuse distribution of receptors in extrasynaptic membranes is a default state or is actively controlled remains essentially unknown. Here we
A highly secreted sulphamidase engineered to cross the blood-brain barrier corrects brain lesions of mice with mucopolysaccharidoses type IIIA
Sorrentino NC, et al.
EMBO Molecular Medicine, 5(5), 675-690 (2013)

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Instructions

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