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Merck

C7956

Coenzyme Q1

≥95%

동의어(들):

2,3-Dimethoxy-5-methyl-6-(3-methyl-2-butenyl)-1,4-benzoquinone, Ubiquinone-1, Ubiquinone-5

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C14H18O4
CAS 번호:
Molecular Weight:
250.29
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:
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InChI

1S/C14H18O4/c1-8(2)6-7-10-9(3)11(15)13(17-4)14(18-5)12(10)16/h6H,7H2,1-5H3

SMILES string

COC1=C(OC)C(=O)C(C\C=C(\C)C)=C(C)C1=O

InChI key

SOECUQMRSRVZQQ-UHFFFAOYSA-N

assay

≥95%

form

liquid

storage temp.

−20°C

Quality Level

General description

Coenzyme Q (CoQ) is localized to the hydrophobic domain of the phospholipid bilayer of mitochondria, plasma lipoproteins, and other biological membranes. It is a ubiquinone homolog with a short isoprenoid side chain.

Application

Coenzyme Q1 has been used to measure the mitochondrial respiratory chain complex 1 activity.

Biochem/physiol Actions

Coenzyme Q1 (CoQ1) is a 1 isoprenyl group (not naturally occurring) member of a family of ubiquinones that share a quinine chemical group but differ in the number of isoprenyl chemical subunits in their tail. The CoQ compounds are lipid soluble components of cell membranes where they perform multiple functions such as electron and proton transport. The most well studied CoQ compound is CoQ10. CoQ1 is frequently used in comparison studies on the effect of isoprenyl chain length on CoQ functions or distribution and to identify quinone reductases.

Other Notes

Analog of coenzyme Q10 (not naturally occurring)

저장 등급

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Nature, 557(7703), 123-126 (2018-04-27)
Alternative complex III (ACIII) is a key component of the respiratory and/or photosynthetic electron transport chains of many bacteria1-3. Like complex III (also known as the bc1 complex), ACIII catalyses the oxidation of membrane-bound quinol and the reduction of cytochrome
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Phase II conjugation of phenolic compounds constitutes an important mechanism through which exogenous or endogenous toxins are detoxified and excreted. Species differences in the rates of glucuronidation or sulfation can lead to significant variation in the metabolism of this class
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The lipid compositions of various regions of the human brain were investigated during aging and in Alzheimer's disease. The phospholipid amounts and compositions remained unchanged during aging. There were, however, considerable differences both in phospholipid composition and amount when the
Alfonso Varela-López et al.
Molecules (Basel, Switzerland), 21(3), 373-373 (2016-03-22)
Coenzyme Q (CoQ) is a naturally occurring molecule located in the hydrophobic domain of the phospholipid bilayer of all biological membranes. Shortly after being discovered, it was recognized as an essential electron transport chain component in mitochondria where it is

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