C9301
Chicken Collagen Type II
from chicken sternal cartilage, powder, suitable for cell culture
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
제품정보 (DICE 배송 시 비용 별도)
Biological source:
chicken (Sternal cartilage)
Form:
powder
Technique(s):
cell culture | mammalian: suitable
Concentration:
60-80% (biuret)
제품 이름
Collagen from chicken sternal cartilage, Type II (Miller), powder, BioReagent, suitable for cell culture
biological source
chicken (Sternal cartilage)
type
Type II (Miller)
product line
BioReagent
form
powder
packaging
glass bottle of 100 mg, poly bottle of 25 mg, glass bottle of 5 mg
concentration
60-80% (biuret)
technique(s)
cell culture | mammalian: suitable
surface coverage
6‑10 μg/cm2
solubility
acetic acid: 0.5-2.0 mg/mL (Dissolve for several hours at 2-8 °C, occasionally swirling.)
UniProt accession no.
binding specificity
Peptide Source: Fibrinogen
shipped in
wet ice
storage temp.
2-8°C
Quality Level
Gene Information
chicken ... COL2A1(395069)
Application
Collagen from chicken sternal cartilage has been used:
- in enzyme–linked immunosorbent assay (ELISA).
- chondrocyte-mediated tissue production in vitro.
- induction, treatment, and assessment of collagenα induced arthritis (CIA).
- cell proliferation assay.
- as a coating for cell culture surfaces.
Biochem/physiol Actions
Collagen breaks down metabolically in the body to release N-telopeptide, which is the N-terminus of collagen. There is also C-telopeptide, which is presumably the C-terminus. N-telopeptide is released in urine, and its detection in diagnostic tests is used to screen for osteoporosis.
Features and Benefits
This collagen has been tested in culture with mammalian cells to verify it is low in endotoxin content.
General description
Collagen is classified into a number of structurally and genetically distinct types. We use the nomenclature proposed by Bornstein and Traub. Do not confuse Sigma type designations with recognized collagen classification types.
Collagen is made of three polypeptide chains. Type 2 collagen is ubiquitously present in the hyaline cartilage. It is a homotrimer made of three α1 chains. Type 2 collagen is also predominant in nucleus pulposus of the vertebral disc and vitreous body of the eye. The proteoglycan obtained from the chicken sternal cartilage is similar to type nine collagen structure.
Other Notes
Major component of articular cartilage.
Preparation Note
Prepared by a modification of the method of Trentham, D.E., et al.
저장 등급
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Mesenchymal-Epithelial Interactions in Neural Development (2013)
Biology of Proteoglycans (2013)
Cytokine profiles in the joint depend on pathology, but are different between synovial fluid, cartilage tissue and cultured chondrocytes.
Tsuchida A I, et al.
Arthritis Research & Therapy, 16(5), 441-441 (2014)
Derivation of Chondrogenic Cells from Human Embryonic Stem Cells for Cartilage Tissue Engineering
Toh W S
Methods in Molecular Biology (2014)
High-density lipoproteins attenuate high glucose-impaired endothelial cell signaling and functions: potential implications for improved vascular repair in diabetes.
Chen X, et al.
Cardiovascular Diabetology, 16(1), 121-121 (2017)
문서
Cancer stem cell media, spheroid plates and cancer stem cell markers to culture and characterize CSC populations.
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.