D0815
2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide
≥99% purity (HPLC), solid
동의어(들):
DASPEI
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C17H21IN2
CAS 번호:
Molecular Weight:
380.27
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
223-248-3
MDL number:
Beilstein/REAXYS Number:
3783243
제품 이름
2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide, ≥99% (HPLC), solid
InChI
1S/C17H21N2.HI/c1-4-19-14-6-5-7-17(19)13-10-15-8-11-16(12-9-15)18(2)3;/h5-14H,4H2,1-3H3;1H/q+1;/p-1
SMILES string
[I-].CC[n+]1ccccc1\C=C\c2ccc(cc2)N(C)C
InChI key
AMAXNNVXIBDEMV-UHFFFAOYSA-M
assay
≥99% (HPLC)
form
solid
color
red
mp
267 °C (dec.) (lit.)
solubility
DMSO: 0.5 mg/mL, methanol: soluble
εmax
36.0-41.0 at 457-463 nm in methanol
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
2-8°C
Quality Level
Application
2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide (DASPEI) has been used for the labelling of hair cells in larval zebrafish.
Biochem/physiol Actions
2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide (DASPEI) accumulates in the mitochondria and has a large fluorescence Stokes shift. It is also used for the relative measurements of mitochondrial membrane potential.
Suitable as a mitochondrial stain in live cells.
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Ru Zhang et al.
Biomolecules, 10(10) (2020-10-22)
Cochlear hair cells in human beings cannot regenerate after loss; however, those in fish and other lower species can. Recently, the role of inflammation in hair cell regeneration has been attracting the attention of scientists. In the present study, we
Development of a no-wash assay for mitochondrial membrane potential using the styryl dye DASPEI.
Jensen KH and Rekling JC
Journal of Biomolecular Screening, 15, 1071-1081 (2010)
Marina Yoffe et al.
Journal of experimental zoology. Part B, Molecular and developmental evolution, 334(7-8), 511-517 (2020-05-22)
The lateral line is the primary modality fish use to create a hydrodynamic image of their environment. These images contribute to a variety of behaviors, from rheotaxis to escape responses. Here we discern the contributions of visual and lateral line
Screen of FDA-approved drug library reveals compounds that protect hair cells from aminoglycosides and cisplatin.
Vlasits AL, et al.
Hearing Research, 294, 153-165 (2012)
S D McCormick
The American journal of physiology, 259(4 Pt 2), R857-R863 (1990-10-01)
Opercular membranes from freshwater tilapia (Oreochromis mossambicus) were maintained in vitro for 4 days and exposed to several concentrations of cortisol (0, 0.01, 0.1, 1, and 10 micrograms/ml). Chloride cell size, number, and Na(+)-K(+)-ATPase content were examined using a fluorescent
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