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Merck

D2510

Deoxycholic acid

≥98% (HPLC)

동의어(들):

3α,12α-Dihydroxy-5β-cholanic acid, 7-Deoxycholic acid, Desoxycholic acid

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C24H40O4
CAS 번호:
83-44-3
Molecular Weight:
392.57
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
24893692
EC Number:
201-478-5
Beilstein/REAXYS Number:
3219882
MDL number:
MFCD00003673

주요 문서

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제품 이름

Deoxycholic acid, ≥98% (HPLC)

InChI key

KXGVEGMKQFWNSR-LLQZFEROSA-N

InChI

1S/C24H40O4/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-/m1/s1

SMILES string

C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

biological source

bovine bile (ex gall bladder)

description

anionic

assay

≥98% (HPLC)

form

powder

mol wt

392.57 g/mol

mp

171-174 °C (lit.)

functional group

carboxylic acid

shipped in

ambient

storage temp.

room temp

Quality Level

200

Gene Information

human ... ATIC(471)

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관련 카테고리

Application

Deoxycholic acid has been used in a study to assess a pH-Responsive Mechanism of a Deoxycholic Acid and Folate Co-Modified Chitosan Micelle under Cancerous Environment. It has also been used in a study to investigate dose-dependent anti-inflammatory effect of ursodeoxycholic acid in experimental colitis.

Biochem/physiol Actions

Bile Acid

General description

Deoxycholic acid is a proinflammatory agent.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
BCCM5518
BCCL7459
BCCL0189
BCCH8920
BCCG6672

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COA 검색

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문서 라이브러리 방문

pH-Responsive Mechanism of a Deoxycholic Acid and Folate Co-Modified Chitosan Micelle under Cancerous Environment
Chen, D., et al.
The Journal of Physical Chemistry B, 1261-1268 (2013)
Patricia Martínez-Moya et al.
International immunopharmacology, 15(2), 372-380 (2012-12-19)
The denomination of inflammatory bowel disease comprises a group of chronic inflammatory diseases of the digestive tract, ulcerative colitis and Crohn's disease being the most important conditions. Bile acids may play a role both in etiology and pharmacology of this
Thierry Claudel et al.
Arteriosclerosis, thrombosis, and vascular biology, 25(10), 2020-2030 (2005-07-23)
Bile acids are the end products of cholesterol metabolism. They are synthesized in the liver and secreted via bile into the intestine, where they aid in the absorption of fat-soluble vitamins and dietary fat. Subsequently, bile acids return to the
Jeffery L Smith et al.
Hepatology (Baltimore, Md.), 39(6), 1673-1682 (2004-06-09)
Focal biliary cirrhosis causes significant morbidity and mortality in cystic fibrosis (CF). Although the mechanisms of pathogenesis remain unclear, bile acids have been proposed as potential mediators of liver injury. This study examined bile acid composition in CF and assessed
J Stadler et al.
Cancer letters, 38(3), 315-320 (1988-01-01)
Rectal biopsies and fecal collections were obtained from a consecutive series of 34 outpatients prior to colonoscopy at a gastroenterology clinic. Subsequently, 14 were found to have no colonic pathology, 13 had adenomatous polyps, (3 of those had a previous
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프로토콜

HPLC Separation of Bile Acids with Ascentis Express C18

Investigate bile acid roles in gut hormone profiles and glycemic control, vital for clinical labs exploring potential mechanisms.

관련 콘텐츠

Bile Acids Kit for LC-MS

Bile Acids (BA) are synthesized in the liver and play important roles in cholesterol homeostasis, absorption of vitamins and lipids, and various key metabolic processes.

Product Information Sheet - D2510

Product Information Sheet

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

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