biological source
bacterial (Leuconostoc mesenteroides)
form
powder
extent of labeling
~3.2% nitrogen
useful pH range
4.0 - 6.0
solubility
H2O: soluble 100 mg/mL, clear, colorless to faintly yellow
storage temp.
room temp
Quality Level
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Application
DEAE-Dextran 500, a polycationic stabilizing molecule and transfection reagent, is used in the development of sustained release protein delivery and nucleic acid transfection systems. DEAE-Dextran 500 may be used for cell immobilization in biosensors.
Other Notes
To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
DEAE-dextran transfection of mammalian cultured cells.
E T Schenborn et al.
Methods in molecular biology (Clifton, N.J.), 130, 147-153 (1999-12-10)
Shingo Kikuchi et al.
International journal of pharmaceutics, 386(1-2), 149-155 (2009-11-20)
A multivariate statistical technique was applied to designing a tablet for the sustained release over 24h of diltiazem hydrochloride, a model highly water-soluble drug. Tablets of a hydrophilic matrix composed of dextran derivatives and hypromellose were prepared. The formulations were
Nattamon Niyomdecha et al.
Heliyon, 6(6), e04050-e04050 (2020-06-13)
Niclosamide has been known to inhibit a number of pH-dependent viruses via the neutralization of endosomal acidic pH. It has also been shown to disrupt the mTORC1 signaling pathway. The replication of many viruses requires mTORC1 activation. Here, we investigated
Bhawna Yadav et al.
Cell surface (Amsterdam, Netherlands), 6, 100042-100042 (2020-12-29)
We designed experiments to assess whether fungal cell wall mannans function as an immune shield or an immune agonist. Fungal cell wall β-(1,3)-glucan normally plays a major and dominant role in immune activation. The outer mannan layer has been variously
J Zarate et al.
Journal of microencapsulation, 28(7), 614-620 (2011-07-12)
Bovine serum albumin (BSA) loaded calcium alginate microparticles (MPs) produced in this study by a w/o emulsification and external gelation method exhibited spherical and fairly smooth and porous morphology with 1.052 ± 0.057 µm modal particle size. The high permeability of the calcium
문서
Explore how carbohydrates function as excipients and carriers in drug delivery, with insights into mechanisms, case studies, and future trends.
Discover the role of carbohydrates in drug delivery, from solubility and stability improvement to advanced controlled-release systems.
관련 콘텐츠
Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.
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